SCHEMBL28840340

SCHEMBL28840340

Cc1ccccc1C#CSCc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 7/20 0.41
FFAR4 Q5NUL3 2/20 0.41
CHRM2 P08172 1/20 0.41
S1PR1 P21453 1/20 0.41
FPR1 P21462 1/20 0.41
FPR3 P25089 1/20 0.41
GPR183 P32249 1/20 0.41
APLNR P35414 1/20 0.41
GPR65 Q8IYL9 1/20 0.41
TSHR P16473 1/20 0.39
MAPK1 P28482 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
RAB9A P51151 2/20 0.38
NPC1 O15118 1/20 0.38
EGFR P00533 1/20 0.38
HPGD P15428 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
GRM5 P41594 1/20 0.36
ALDH1A1 P00352 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL44259 0.76 IDO1 (0.44) TSHRALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL28359780 0.75 PAM (0.55) FFAR1FFAR4RAB9ANPC1CYP1A2
SCHEMBL9217746 0.72 MAOB (0.44) EGFRCYP1A2CYP3A4CYP2D6PRMT1
SCHEMBL28993730 0.72 TSHR (0.43) FFAR1FFAR4CHRM2S1PR1FPR1
SCHEMBL30666154 0.71 TSHR (0.62) FFAR1FFAR4CHRM2S1PR1FPR1
SCHEMBL3644208 0.71 TSHR (0.62) FFAR1FFAR4CHRM2S1PR1FPR1
SCHEMBL28420190 0.69 TP53 (0.41) RAB9ACYP1A2CYP3A4CYP2D6PRMT1
SCHEMBL23088675 0.68 EGFR (0.39) MAPK1TDP1RAB9ANPC1EGFR
SCHEMBL28902312 0.68 CYP2D6 (0.44) EGFRALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL10978005 0.68 CYP1A2 (0.42) RAB9ACYP1A2CYP3A4CYP2D6PRMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115044923-A Method for preparing 2-aryl-3-thiocyano-benzothiophene by using electrochemical reaction 盐城师范学院 2022-09-13 CN disclosed