SCHEMBL28360337 — predicted protein targets

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	L3MBTL1	Q9Y468	2/20	0.40

▸	RECQL	P46063	1/20	0.40

▸	ALDH1A1	P00352	5/20	0.40

▸	SMN1; SMN2	Q16637	2/20	0.39

▸	MAPT	P10636	2/20	0.39

▸	GAA	P10253	2/20	0.39

▸	HPGD	P15428	1/20	0.39

▸	KMT2A	Q03164	1/20	0.37

▸	F2R	P25116	1/20	0.37

▸	LMNA	P02545	1/20	0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL20539950	0.78	L3MBTL1 (0.46)	L3MBTL1RECQLALDH1A1SMN1; SMN2MAPT
SCHEMBL28616072	0.77	SMN1; SMN2 (0.46)	L3MBTL1RECQLALDH1A1SMN1; SMN2MAPT
SCHEMBL30577136	0.77	SMN1; SMN2 (0.46)	L3MBTL1RECQLALDH1A1SMN1; SMN2MAPT
SCHEMBL28921340	0.75	SMN1; SMN2 (0.45)	L3MBTL1RECQLALDH1A1SMN1; SMN2MAPT
SCHEMBL24613319	0.74	MEN1 (0.41)	L3MBTL1RECQLALDH1A1GAAKMT2A
SCHEMBL29724468	0.74	MEN1 (0.41)	L3MBTL1RECQLALDH1A1GAAKMT2A
SCHEMBL18190399	0.73	P2RX7 (0.50)	ALDH1A1SMN1; SMN2MAPTGAAHPGD
SCHEMBL27316128	0.71	NPC1 (0.56)	L3MBTL1ALDH1A1SMN1; SMN2MAPTGAA
SCHEMBL27007827	0.70	NPC1 (0.68)	L3MBTL1ALDH1A1SMN1; SMN2MAPTGAA
SCHEMBL28610687	0.70	HDAC8 (0.48)	ALDH1A1SMN1; SMN2GAAHPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-110799509-A	PD-1/PD-L1 inhibitors	吉利德科学公司	2020-02-14	—	—	CN	disclosed