Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | HTT | P42858 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30577136 | 1.00 | SMN1; SMN2 (0.46) | SMN1; SMN2KMT2ANPC1MEN1ALDH1A1 | |
| SCHEMBL20539950 | 0.83 | L3MBTL1 (0.46) | SMN1; SMN2ALDH1A1GAAMAPTHPGD | |
| SCHEMBL28921340 | 0.80 | SMN1; SMN2 (0.45) | SMN1; SMN2KMT2AMEN1ALDH1A1HTT | |
| SCHEMBL18729343 | 0.80 | MAPT (0.47) | ALDH1A1HTTGAARAB9AMAPT | |
| SCHEMBL30395214 | 0.80 | MAPT (0.47) | ALDH1A1HTTGAARAB9AMAPT | |
| SCHEMBL19897775 | 0.78 | HPGD (0.50) | SMN1; SMN2KMT2AMEN1ALDH1A1HTT | |
| SCHEMBL30394063 | 0.78 | HPGD (0.50) | SMN1; SMN2KMT2AMEN1ALDH1A1HTT | |
| SCHEMBL6769122 | 0.78 | SMN1; SMN2 (0.67) | SMN1; SMN2NPC1ALDH1A1GAARAB9A | |
| SCHEMBL28360337 | 0.77 | L3MBTL1 (0.40) | SMN1; SMN2KMT2AALDH1A1GAAMAPT | |
| SCHEMBL18190399 | 0.77 | P2RX7 (0.50) | SMN1; SMN2KMT2ANPC1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116730940-A | Heterocyclic substituted biphenyl compound and medical application thereof | 中国药科大学 | 2023-09-12 | — | — | CN | disclosed |
| CN-113307779-A | Heterocyclic substituted biphenyl compound, preparation method and application | 中国药科大学 | 2021-08-27 | — | — | CN | disclosed |