Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29154325 | 1.00 | LMNA (0.45) | LMNASMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL4304419 | 0.86 | MIF (0.45) | LMNASMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL4305863 | 0.86 | MIF (0.45) | LMNASMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL11928961 | 0.86 | MIF (0.45) | LMNASMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL23345343 | 0.85 | KMT2A (0.58) | SMN1; SMN2NPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL1769121 | 0.85 | KMT2A (0.58) | SMN1; SMN2NPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL28849826 | 0.85 | PTGS2 (0.51) | LMNASMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL6060573 | 0.85 | PTGS2 (0.51) | LMNASMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL19020191 | 0.85 | HPGD (0.47) | LMNASMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL28634821 | 0.85 | CYP1A2 (0.50) | LMNASMN1; SMN2NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117551025-A | Preparation method of 4, 4-dicyano-2-alkyl-pyrrolidine-2-carboxylic ester derivative | 华北水利水电大学 | 2024-02-13 | — | — | CN | disclosed |
| CN-114940661-B | Camphora-reducing derived [2, 1] -bridged cyclic enones compound and synthesis method and application thereof | 武汉大学 | 2023-12-22 | — | — | CN | disclosed |
| CN-113461690-B | Synthesis method of chiral 4,6-dioxooctahydropyrrolo [3,4-c ] pyrrole-1-carboxylate compound | 中国科学院大连化学物理研究所 | 2023-03-31 | — | — | CN | disclosed |
| CN-110577485-B | Norcamphor derived [2, 1] -bridged ring ketene compounds and synthesis method and application thereof | 武汉大学 | 2022-11-04 | — | — | CN | disclosed |
| CN-114940661-A | Norcamphor derived [2,2,1] -bridged ketene compounds and synthesis method and application thereof | 武汉大学 | 2022-08-26 | — | — | CN | disclosed |
| CN-113461690-A | Synthesis method of chiral 4, 6-dioxooctahydropyrrolo [3,4-c ] pyrrole-1-carboxylic ester compound | 中国科学院大连化学物理研究所 | 2021-10-01 | — | — | CN | disclosed |
| CN-110669046-B | Polysubstituted tetrahydro-gamma-carboline derivative with multiple chiral centers and preparation method of stereo diversity of polysubstituted tetrahydro-gamma-carboline derivative | 武汉大学 | 2021-07-06 | — | — | CN | disclosed |
| CN-110669046-A | Polysubstituted tetrahydro-gamma-carboline derivative with multiple chiral centers and preparation method of stereo diversity of polysubstituted tetrahydro-gamma-carboline derivative | 武汉大学 | 2020-01-10 | — | — | CN | disclosed |