Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.42 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CDK4 | P11802 | 1/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.42 |
| ▸ | CCND1 | P24385 | 1/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27334104 | 0.80 | KDM4E (0.49) | ALDH1A1KDM4ERXFP1MEN1HSP90AA1 | |
| SCHEMBL3301442 | 0.80 | RAB9A (0.55) | ALDH1A1KDM4EKMT2ARAB9ANPC1 | |
| SCHEMBL9753842 | 0.80 | PTGS1 (0.59) | ALDH1A1KDM4ERXFP1MEN1HSP90AA1 | |
| SCHEMBL1105925 | 0.79 | ALDH1A1 (0.54) | ALDH1A1KDM4ERXFP1MEN1HSP90AA1 | |
| SCHEMBL4781728 | 0.75 | ALDH1A1 (0.53) | ALDH1A1KDM4ERXFP1MEN1HSP90AA1 | |
| SCHEMBL8607526 | 0.75 | KDM4E (0.47) | ALDH1A1KDM4ERXFP1MEN1HSP90AA1 | |
| SCHEMBL4726717 | 0.75 | ALDH1A1 (0.68) | ALDH1A1KDM4ERXFP1MEN1HSP90AA1 | |
| SCHEMBL16739619 | 0.75 | KDM4E (0.50) | ALDH1A1KDM4ERXFP1MEN1HSP90AA1 | |
| SCHEMBL2087968 | 0.73 | PTGS1 (0.51) | ALDH1A1KDM4ERXFP1MEN1HSP90AA1 | |
| Bromide SCHEMBL2087132 | 0.72 | PTGS1 (0.50) | ALDH1A1KDM4ERXFP1MEN1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025076501-A1 | HIGH THROUGHPUT PARALLEL SYNTHESIS OF SMALL MOLECULE DEGRADERS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2025-04-10 | — | — | WO | disclosed |
| CN-110799509-A | PD-1/PD-L1 inhibitors | 吉利德科学公司 | 2020-02-14 | — | — | CN | disclosed |