Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 2/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | ALKBH5 | Q6P6C2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LDHA | P00338 | 2/20 | 0.32 |
| ▸ | LDHB | P07195 | 2/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4868173 | 0.86 | L3MBTL1 (0.38) | AURKAAURKBTDP1L3MBTL1HPGD | |
| SCHEMBL28122101 | 0.81 | HAAO (0.38) | AURKAAURKBTDP1L3MBTL1HPGD | |
| SCHEMBL7404074 | 0.80 | LDHA (0.43) | HPGDALDH1A1MEN1KMT2ALDHA | |
| SCHEMBL13533501 | 0.78 | GPR35 (0.49) | ALDH1A1MEN1KMT2A | |
| SCHEMBL3101612 | 0.77 | GLRA3 (0.41) | AURKAAURKBTDP1L3MBTL1NOTUM | |
| SCHEMBL27324755 | 0.76 | TDP1 (0.39) | AURKAAURKBTDP1L3MBTL1HPGD | |
| SCHEMBL29693892 | 0.76 | TDP1 (0.39) | TDP1L3MBTL1NOTUMALDH1A1CYP3A4 | |
| SCHEMBL1085313 | 0.76 | TDP1 (0.39) | TDP1L3MBTL1NOTUMALDH1A1CYP3A4 | |
| SCHEMBL27484681 | 0.76 | TDP1 (0.36) | AURKAAURKBTDP1L3MBTL1NOTUM | |
| SCHEMBL28097596 | 0.75 | MYC (0.40) | TDP1L3MBTL1HPGDALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110498759-A | The synthetic method of isoindoline ketone compound | TIANJIN RUILING CHEMICAL CO LTD | 2019-11-26 | — | — | CN | disclosed |