Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 6/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.31 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28361049 | 0.91 | ADORA2A (0.33) | ADORA2AADORA1ADORA2BGRM5KMT2A | |
| SCHEMBL28360928 | 0.89 | ADORA2A (0.44) | ADORA2AADORA1ADORA2BKMT2A | |
| SCHEMBL9649735 | 0.81 | ACHE (0.35) | — | |
| SCHEMBL7024108 | 0.81 | DYRK1A (0.40) | — | |
| SCHEMBL9784283 | 0.79 | ACHE (0.30) | — | |
| SCHEMBL4453497 | 0.78 | NOTUM (0.32) | — | |
| SCHEMBL28357412 | 0.78 | ADORA2A (0.32) | ADORA2AADORA1ADORA2BKMT2A | |
| SCHEMBL9648734 | 0.77 | ACHE (0.41) | KMT2ARAB9ANPC1SMN1; SMN2HTT | |
| SCHEMBL9649334 | 0.76 | CYP3A4 (0.33) | — | |
| SCHEMBL5797082 | 0.74 | MAOB (0.35) | RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110809577-A | Modulators of adenosine A2A receptor | 雷沃医疗有限公司 | 2020-02-18 | — | — | CN | claimed |
| CN-110809577-A | Modulators of adenosine A2A receptor | 雷沃医疗有限公司 | 2020-02-18 | — | — | CN | disclosed |