Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 3/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28360928 | 0.89 | ADORA2A (0.44) | ADORA2AADORA1ADORA3ADORA2BMAPT | |
| SCHEMBL9649089 | 0.81 | TSHR (0.32) | — | |
| SCHEMBL28357070 | 0.81 | IDO1 (0.38) | ADORA2AADORA1 | |
| SCHEMBL4453497 | 0.78 | NOTUM (0.32) | — | |
| SCHEMBL28360899 | 0.78 | ADORA2A (0.38) | ADORA2AADORA1ADORA2BKMT2A | |
| SCHEMBL436469 | 0.77 | NOTUM (0.38) | — | |
| SCHEMBL28357214 | 0.76 | ALDH1A1 (0.35) | MEN1MAPTKMT2A | |
| SCHEMBL9649334 | 0.76 | CYP3A4 (0.33) | — | |
| SCHEMBL22463151 | 0.74 | AHR (0.46) | MEN1MAPTKMT2A | |
| SCHEMBL5797082 | 0.74 | MAOB (0.35) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110809577-A | Modulators of adenosine A2A receptor | 雷沃医疗有限公司 | 2020-02-18 | — | — | CN | claimed |
| CN-110809577-A | Modulators of adenosine A2A receptor | 雷沃医疗有限公司 | 2020-02-18 | — | — | CN | disclosed |