SCHEMBL4453497

SCHEMBL4453497

Fc1cc[c]c(-c2cc(F)cc(F)c2)c1

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.32
CYP1A2 P05177 1/20 0.30
CYP2A6 P11509 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1205892 0.83 TAAR1 (0.44) NOTUM
SCHEMBL5797082 0.82 MAOB (0.35) CYP1A2CYP2A6
SCHEMBL2013527 0.81 GABRP (0.30)
SCHEMBL2013006 0.81 ACHE (0.35)
SCHEMBL9649735 0.81 ACHE (0.35)
SCHEMBL9649089 0.81 TSHR (0.32)
SCHEMBL5093327 0.80 MAOB (0.35) CYP1A2CYP2A6
SCHEMBL9784283 0.79 ACHE (0.30)
SCHEMBL2013705 0.78 RXRA (0.33)
SCHEMBL5796805 0.77 ESR2 (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1865006-B1 Propylene polymer and composition containing the same, molded object and laminate comprising these, and processes for producing propylene polymer and composition containing the same IDEMITSU KOSAN CO (JP) 2009-06-24 EP disclosed