Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 1/20 | 0.35 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.35 |
| ▸ | FADS1 | O60427 | 4/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28361061 | 0.94 | FADS1 (0.37) | CSNK1DCSNK1EFADS1NPC1RAB9A | |
| SCHEMBL17926042 | 0.89 | FADS1 (0.36) | FADS1HTR6HSD11B1ROCK2ROCK1 | |
| SCHEMBL21432168 | 0.87 | FADS1 (0.36) | FADS1HTR6NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28357469 | 0.86 | CSNK1D (0.36) | CSNK1DCSNK1ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28361064 | 0.86 | CSNK1D (0.36) | CSNK1DCSNK1EHTR6NPC1RAB9A | |
| SCHEMBL17926213 | 0.82 | FADS1 (0.34) | FADS1ROCK2 | |
| SCHEMBL17925737 | 0.81 | AR (0.35) | — | |
| SCHEMBL28357358 | 0.80 | GRM4 (0.42) | CSNK1DCSNK1EGRIN2B | |
| SCHEMBL28361041 | 0.79 | CSNK1D (0.36) | CSNK1DCSNK1ENPC1RAB9AGRIN2B | |
| SCHEMBL19860148 | 0.79 | FADS1 (0.32) | FADS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110804061-B | Pyrazole and pyrazine formamide compound containing cyclopropyl segment and application thereof | 中国医学科学院医药生物技术研究所 | 2021-01-05 | — | — | CN | disclosed |
| CN-110804061-A | Pyrazole and pyrazine formamide compound containing cyclopropyl segment and application thereof | 中国医学科学院医药生物技术研究所 | 2020-02-18 | — | — | CN | disclosed |