SCHEMBL283611

SCHEMBL283611

COC(=O)C(SSC(C(=O)OC)c1ccccc1)c1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.62
LMNA P02545 2/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
MEN1 O00255 2/20 0.46
PTGS1 P23219 1/20 0.46
PTGS2 P35354 1/20 0.46
ALDH1A1 P00352 1/20 0.46
MAPT P10636 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
PKM P14618 1/20 0.44
TSHR P16473 2/20 0.43
CTSD P07339 1/20 0.42
SLC6A3 Q01959 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1578734 0.86 KMT2A (0.60) KMT2ALMNASMN1; SMN2NPSR1MEN1
SCHEMBL27864446 0.85 KMT2A (0.58) KMT2ALMNASMN1; SMN2NPSR1MEN1
SCHEMBL20540763 0.83 LMNA (0.65) KMT2ALMNASMN1; SMN2NPSR1MEN1
SCHEMBL11780897 0.81 KDM4E (0.57) KMT2ASMN1; SMN2MEN1TDP1PKM
SCHEMBL16841424 0.80 KMT2A (0.53) KMT2ALMNASMN1; SMN2NPSR1MEN1
SCHEMBL8443134 0.79 KMT2A (0.51) KMT2ALMNASMN1; SMN2NPSR1MEN1
SCHEMBL2893483 0.79 KMT2A (0.51) KMT2ALMNASMN1; SMN2NPSR1MEN1
SCHEMBL237873 0.79 KMT2A (0.51) KMT2ALMNASMN1; SMN2NPSR1MEN1
SCHEMBL28521355 0.78 SMN1; SMN2 (0.52) KMT2ALMNASMN1; SMN2NPSR1MEN1
SCHEMBL5424343 0.78 LMNA (0.54) KMT2ALMNASMN1; SMN2NPSR1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8592356-B2 Lubricant composition for internal combustion engine IDEMITSU KOSAN CO., LTD. (JP) 2013-11-26 US claimed
US-8309499-B2 Lubricant composition for internal combustion engine IDEMITSU KOSAN CO., LTD. (JP) 2012-11-13 US claimed
US-20210214637-A1 LUBRICANT COMPOSITION IDEMITSU KOSAN CO.,LTD. (JP) 2021-07-15 US disclosed
EP-3795663-A1 LUBRICANT COMPOSITION Idemitsu Kosan Co.,Ltd. (JP) 2021-03-24 EP disclosed
CN-112088206-A Lubricating oil composition 出光兴产株式会社 2020-12-15 CN disclosed
EP-2280057-B2 LUBRICATING OIL COMPOSITION FOR INTERNAL COMBUSTION ENGINE IDEMITSU KOSAN CO (JP) 2016-11-23 EP disclosed
US-20160257902-A1 LUBRICATING OIL COMPOSITION IDEMITSU KOSAN CO., LTD. (JP) 2016-09-08 US disclosed
EP-3064564-A1 LUBRICATING OIL COMPOSITION Idemitsu Kosan Co., Ltd (JP) 2016-09-07 EP disclosed
CN-105683344-A Lubricating oil composition 出光兴产株式会社 2016-06-15 CN disclosed
US-9321981-B2 Lubricating oil composition for internal combustion engine IDEMITSU KOSAN CO., LTD. (JP) 2016-04-26 US disclosed
CN-103781888-B Biodegradable lubricating oil composition IDEMITSU KOSAN CO.,LTD. (JP) 2016-01-13 CN disclosed
EP-2157160-A1 LUBRICANT COMPOSITION FOR INTERNAL COMBUSTION ENGINE Idemitsu Kosan Co., Ltd. (JP) 2010-02-24 EP disclosed
US-20100009880-A1 LUBRICATING OIL COMPOSITION IDEMITSU KOSAN CO., LTD. (JP) 2010-01-14 US disclosed
US-20100009882-A1 LUBRICATING OIL COMPOSITION FOR INTERNAL COMBUSTION ENGINE IDEMITSU KOSAN CO., LTD (JP) 2010-01-14 US disclosed
US-20090203561-A1 LUBRICANT COMPOSITION FOR INTERNAL COMBUSTION ENGINE IDEMITSU KOSAN CO., LTD. (JP) 2009-08-13 US disclosed
EP-2067846-A1 LUBRICATING OIL COMPOSITION Idemitsu Kosan Co., Ltd. (JP) 2009-06-10 EP disclosed
EP-2060619-A1 LUBRICANT COMPOSITION FOR INTERNAL COMBUSTION ENGINE IDEMITSU KOSAN CO., LTD. (JP) 2009-05-20 EP disclosed
US-20060148663-A1 Additives for lubricating oils and fuel oils, lubricating oil compositions, and fuel oil compositions IDEMITSU KOSAN CO., LTD. (JP) 2006-07-06 US disclosed
EP-1602709-A1 ADDITIVES FOR LUBRICATING OILS AND FUEL OILS, LUBRICATING OIL COMPOSITIONS, AND FUEL OIL COMPOSITIONS IDEMITSU KOSAN CO., LTD. (JP) 2005-12-07 EP disclosed
US-4085094-A SULFENYLTHIOCARBONATES THE GOODYEAR TIRE & RUBBER COMPANY (US) 1978-04-18 US disclosed