SCHEMBL5329159

SCHEMBL5329159

Nc1ccc(C(N)C(=O)O)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 5/20 0.53
TDP1 Q9NUW8 5/20 0.53
MEN1 O00255 3/20 0.53
CYP2C9 P11712 3/20 0.53
KMT2A Q03164 3/20 0.53
CYP2C19 P33261 2/20 0.53
GRM8 O00222 2/20 0.53
GRM4 Q14833 2/20 0.53
CYP2D6 P10635 1/20 0.53
GRM6 O15303 1/20 0.53
SLC6A2 P23975 1/20 0.53
SLC6A4 P31645 1/20 0.53
DRD3 P35462 1/20 0.53
KDM4E B2RXH2 4/20 0.50
ALDH1A1 P00352 4/20 0.50
HPGD P15428 4/20 0.50
GRM1 Q13255 3/20 0.50
GRM2 Q14416 2/20 0.50
GRM7 Q14831 1/20 0.45
POLB P06746 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2262988 1.00 HSD17B10 (0.53) HSD17B10TDP1MEN1CYP2C9KMT2A
Hydrochloric Acid SCHEMBL4688181 0.98 TDP1 (0.52) HSD17B10TDP1MEN1CYP2C9KMT2A
SCHEMBL13527786 0.90 HSD17B10 (0.61) HSD17B10TDP1MEN1CYP2C9KMT2A
SCHEMBL11520882 0.84 HSD17B10 (0.52) HSD17B10TDP1MEN1CYP2C9KMT2A
Oxfenicine SCHEMBL124861 0.81 HSD17B10 (0.55) HSD17B10TDP1MEN1CYP2C9KMT2A
SCHEMBL4872444 0.81 MAPT (0.41) TDP1MEN1KMT2ACYP2C19GRM8
Oxfenicine SCHEMBL652186 0.81 HSD17B10 (0.55) HSD17B10TDP1MEN1CYP2C9KMT2A
Oxfenicine SCHEMBL122315 0.81 HSD17B10 (0.55) HSD17B10TDP1MEN1CYP2C9KMT2A
Phenylglycine SCHEMBL11576917 0.80 CYP2D6 (0.56) HSD17B10TDP1MEN1CYP2C9KMT2A
Phenylglycine SCHEMBL157180 0.80 CYP2D6 (0.56) HSD17B10TDP1MEN1CYP2C9KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2665493-B1 MRI MARKERS, DELIVERY AND EXTRACTION SYSTEMS, AND METHODS OF MANUFACTURE AND USE THEREOF UNIV TEXAS (US) 2018-03-21 EP claimed
CN-103450068-B A kind of synthetic method of Ziprasidone intermediate CHONGQING CHANGJIE MEDICAL CHEMICAL CO., LTD. (CN) 2015-09-16 CN claimed
CN-103450068-A Synthetic method of ziprasidone intermediate CHONGQING CHANGJIE MEDICINE CHEMICAL CO LTD 2013-12-18 CN claimed
CN-1068621-C Polyimide compositions for electrodeposition and coatings formed of the same HIROSHI ITATANI (JP) 2001-07-18 CN claimed
US-5658885-A OLIGOPEPTIDES; ANTICOAGULANTS; ENZYME INHIBITORS; THROMBIN THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) 1997-08-19 US claimed
CN-1154988-A Polyimide compositions for electrodeposition and coatings formed of the same PI MATERIALS RESEARCH LAB (JP) 1997-07-23 CN claimed
US-20260042806-A1 NOVEL PORE MONOMERS AND PORES OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2026-02-12 US disclosed
EP-4569330-A1 NOVEL PORE MONOMERS AND PORES Oxford Nanopore Technologies PLC (GB) 2025-06-18 EP disclosed
CN-119630970-A Novel Kong Shanti and holes 牛津纳米孔科技公开有限公司 2025-03-14 CN disclosed
EP-4433487-A1 CYTARABINE-AMINO ACID BASED PRODRUG FOR THE TREATMENT OF CANCER BioSight Ltd. (IL) 2024-09-25 EP disclosed
WO-2024033443-A1 NOVEL PORE MONOMERS AND PORES OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2024-02-15 WO disclosed
CN-110621695-B anti-JAGGED 1 antigen binding proteins 安进公司 2023-10-17 CN disclosed
WO-2023089617-A1 CYTARABINE-AMINO ACID BASED PRODRUG FOR THE TREATMENT OF CANCER BIOSIGHT LTD. (IL) 2023-05-25 WO disclosed
WO-2001002424-A2 PEPTIDE BORONIC ACID INHIBITORS OF HEPATITIS C VIRUS PROTEASE DU PONT PHARMACEUTICALS COMPANY (US) 2001-01-11 WO disclosed
US-5658885-A OLIGOPEPTIDES; ANTICOAGULANTS; ENZYME INHIBITORS; THROMBIN THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) 1997-08-19 US disclosed
EP-0787010-A1 AMIDINO AND GUANIDINO SUBSTITUTED INHIBITORS OF TRYPSIN-LIKE ENZYMES THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1997-08-06 EP disclosed
WO-1996012499-A1 AMIDINO AND GUANIDINO SUBSTITUTED INHIBITORS OF TRYPSIN-LIKE ENZYMES THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1996-05-02 WO disclosed
EP-0090240-A2 7-Alpha-aminoacyl-3-chlorocephalosporins, their preparation and their use as pharmaceutical products BAYER AG (DE) 1983-10-05 EP disclosed
EP-0049338-A1 Ink for use in ink jet printing International Business Machines Corporation (US) 1982-04-14 EP disclosed
US-4297489-A CEPHALOSPORINS BRISTOL-MYERS COMPANY (US) 1981-10-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260042806-A1 NOVEL PORE MONOMERS AND PORES SCNN1G, CACNG3, ASIC3 HSD17B10 4856/4885TDP1 4238/4885MEN1 991/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.