SCHEMBL28362149

SCHEMBL28362149

C=C(C(=O)O)c1ccc2ccc3ccccc3c2c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.50
MAPT P10636 3/20 0.50
HPGD P15428 3/20 0.50
CASP3 P42574 1/20 0.49
GFER P55789 1/20 0.49
SENP8 Q96LD8 1/20 0.49
SENP7 Q9BQF6 1/20 0.49
SENP6 Q9GZR1 1/20 0.49
HSD17B10 Q99714 5/20 0.47
CYP1B1 Q16678 2/20 0.47
HIF1A Q16665 2/20 0.47
GRIN2D O15399 1/20 0.46
GRIN2A Q12879 1/20 0.46
GRIN2C Q14957 1/20 0.46
CYP1A2 P05177 3/20 0.46
CYP2D6 P10635 3/20 0.46
CYP3A4 P08684 2/20 0.46
CYP1A1 P04798 1/20 0.46
TP53 P04637 2/20 0.46
RAD52 P43351 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11598960 0.83 AKR1B1 (0.54) ALDH1A1MAPTHPGDHSD17B10CYP1B1
SCHEMBL124455 0.83 KDM4E (0.61) ALDH1A1MAPTHPGDHSD17B10CYP1B1
SCHEMBL2469905 0.81 GRIN2D (0.66) ALDH1A1MAPTHPGDCASP3GFER
SCHEMBL28989639 0.80 ALDH1A1 (0.49) ALDH1A1MAPTHPGDCASP3GFER
SCHEMBL15439625 0.78 GRIN2D (0.67) ALDH1A1MAPTHPGDCASP3GFER
SCHEMBL9625019 0.78 NPC1 (0.58) ALDH1A1MAPTHPGDCASP3GFER
SCHEMBL10484184 0.78 GRIN2D (0.67) ALDH1A1MAPTHPGDCASP3GFER
SCHEMBL31742339 0.78 GRIN2D (0.67) ALDH1A1MAPTHPGDCASP3GFER
SCHEMBL23698264 0.77 ALDH1A1 (0.56) ALDH1A1MAPTHPGDCASP3GFER
SCHEMBL28236960 0.76 CYP1B1 (0.54) ALDH1A1MAPTHPGDCASP3GFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110818630-B Synthesis method of conjugated (E) -3-cycloalkenyl acrylate derivative 西南大学 2022-06-10 CN claimed
CN-110818630-B Synthesis method of conjugated (E) -3-cycloalkenyl acrylate derivative 西南大学 2022-06-10 CN disclosed
CN-110818630-A Synthesis method of conjugated (E) -3-cycloalkenyl acrylate derivative 西南大学 2020-02-21 CN disclosed