Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.37 |
| ▸ | ACR | P10323 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28367562 | 0.91 | KIF11 (0.55) | KIF11MEN1KMT2APRSS1ACR | |
| SCHEMBL28364169 | 0.88 | KIF11 (0.55) | KIF11MEN1KMT2APRSS1ACR | |
| SCHEMBL28364204 | 0.80 | KIF11 (0.48) | KIF11MEN1KMT2APRSS1ACR | |
| SCHEMBL28367987 | 0.79 | KIF11 (0.53) | KIF11MEN1KMT2APRSS1ACR | |
| SCHEMBL28459342 | 0.76 | KIF11 (0.66) | KIF11MEN1KMT2APRSS1ACR | |
| SCHEMBL4316832 | 0.76 | KIF11 (0.89) | KIF11MEN1KMT2APRSS1ACR | |
| SCHEMBL28365026 | 0.75 | KIF11 (0.64) | KIF11MEN1KMT2APRSS1ACR | |
| SCHEMBL28909073 | 0.74 | KIF11 (0.86) | KIF11MEN1KMT2APRSS1ACR | |
| SCHEMBL29177337 | 0.73 | KIF11 (0.66) | KIF11MEN1KMT2APRSS1ACR | |
| SCHEMBL4598278 | 0.72 | KIF11 (0.60) | KIF11MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110730780-A | 2, 3-dihydroisoindole-1-carboxamides useful as ROR-gamma modulators | 阿斯利康(瑞典)有限公司 | 2020-01-24 | — | — | CN | disclosed |