Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.42 |
| ▸ | ACR | P10323 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4316832 | 0.84 | KIF11 (0.89) | KIF11KMT2AMEN1PRSS1ACR | |
| SCHEMBL28365026 | 0.83 | KIF11 (0.64) | KIF11KMT2AMEN1PRSS1ACR | |
| SCHEMBL28909073 | 0.82 | KIF11 (0.86) | KIF11KMT2AMEN1PRSS1ACR | |
| SCHEMBL29177337 | 0.81 | KIF11 (0.66) | KIF11KMT2AMEN1PRSS1ACR | |
| SCHEMBL4598278 | 0.80 | KIF11 (0.60) | KIF11KMT2AMEN1 | |
| SCHEMBL6284986 | 0.78 | KMT2A (0.64) | KIF11KMT2AMEN1PRSS1ALDH1A1 | |
| SCHEMBL9575156 | 0.78 | KIF11 (0.41) | KIF11KMT2APRSS1ACRMAOB | |
| SCHEMBL28367788 | 0.78 | KIF11 (0.57) | KIF11KMT2AMEN1PRSS1ACR | |
| SCHEMBL21628511 | 0.77 | PARP10 (0.66) | KMT2APRSS1MAOBALDH1A1CA1 | |
| SCHEMBL28367562 | 0.76 | KIF11 (0.55) | KIF11KMT2AMEN1PRSS1ACR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111533701-B | Synthetic method of pyridine quinazoline intermediate | 湖南速博生物技术有限公司 | 2020-10-16 | — | — | CN | disclosed |
| CN-111533701-A | Synthetic method of pyridine quinazoline intermediate | 湖南速博生物技术有限公司 | 2020-08-14 | — | — | CN | disclosed |