Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | LPL | P06858 | 1/20 | 0.44 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.44 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.44 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.44 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.44 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | WDR5 | P61964 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL350471 | 0.97 | ACHE (0.48) | ACHECA2LPLLIPGORAI1 | |
| SCHEMBL27721550 | 0.95 | ACHE (0.46) | ACHECA2LPLLIPGORAI1 | |
| Ammonia Solution, Strong SCHEMBL27520682 | 0.95 | ACHE (0.46) | ACHECA2LPLLIPGORAI1 | |
| SCHEMBL27659834 | 0.95 | ACHE (0.46) | ACHECA2LPLLIPGORAI1 | |
| SCHEMBL28057019 | 0.95 | ACHE (0.46) | ACHECA2LPLLIPGORAI1 | |
| Trimethylammonium SCHEMBL6458241 | 0.91 | ACHE (0.42) | ACHECA2LPLLIPGORAI1 | |
| SCHEMBL17421190 | 0.85 | CA2 (0.41) | ACHECA2LPLLIPGORAI1 | |
| SCHEMBL3800806 | 0.84 | CA1 (0.38) | CA2TSHRMEN1KMT2ACA1 | |
| SCHEMBL10632841 | 0.82 | ACHE (0.48) | ACHECA2LPLLIPGORAI1 | |
| Toluene SCHEMBL28142692 | 0.81 | LMNA (0.50) | ACHECA2LPLLIPGORAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106687863-B | Passivation layer comprising photo-crosslinked fluoropolymer | 科慕埃弗西有限公司 | 2020-07-10 | — | — | CN | disclosed |
| CN-110885576-A | Preparation method and use method of visible light fast curing organic anti-corrosion environment-friendly coating | 山东非金属材料研究所 | 2020-03-17 | — | — | CN | disclosed |