Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL486240 | 0.84 | RECQL (0.74) | TSHRALDH1A1L3MBTL1POLBHSD17B10 | |
| SCHEMBL28362474 | 0.78 | ALDH1A1 (0.72) | TSHRALDH1A1L3MBTL1POLBHSD17B10 | |
| SCHEMBL28366172 | 0.78 | ALDH1A1 (0.72) | TSHRALDH1A1L3MBTL1POLBHSD17B10 | |
| SCHEMBL486586 | 0.78 | ALDH1A1 (0.72) | TSHRALDH1A1L3MBTL1POLBHSD17B10 | |
| SCHEMBL486053 | 0.77 | ALDH1A1 (0.71) | TSHRALDH1A1L3MBTL1POLBHSD17B10 | |
| SCHEMBL28362330 | 0.77 | L3MBTL1 (1.00) | TSHRALDH1A1L3MBTL1POLBHSD17B10 | |
| SCHEMBL28366142 | 0.75 | ALDH1A1 (0.68) | TSHRALDH1A1L3MBTL1POLBHSD17B10 | |
| SCHEMBL486144 | 0.71 | KMT2A (1.00) | TSHRALDH1A1POLBHSD17B10RECQL | |
| SCHEMBL49648 | 0.71 | MAPT (0.54) | TSHRALDH1A1L3MBTL1POLBHSD17B10 | |
| SCHEMBL20016871 | 0.68 | GAA (0.58) | ALDH1A1POLBHSD17B10HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110713454-A | Nitro-substituted indole compound and preparation method thereof | 南京工业大学 | 2020-01-21 | — | — | CN | claimed |
| CN-110713454-B | Nitro-substituted indole compound and preparation method thereof | 南京工业大学 | 2022-12-09 | — | — | CN | disclosed |
| CN-110713454-A | Nitro-substituted indole compound and preparation method thereof | 南京工业大学 | 2020-01-21 | — | — | CN | disclosed |