SCHEMBL49648

SCHEMBL49648

CC(C)(C)Oc1ccc(Nc2ccc(OC(C)(C)C)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.54
L3MBTL1 Q9Y468 4/20 0.54
GAA P10253 3/20 0.54
RAB9A P51151 3/20 0.54
MAPK1 P28482 3/20 0.54
TDP1 Q9NUW8 3/20 0.54
KDM4E B2RXH2 2/20 0.54
NPC1 O15118 1/20 0.54
THRB P10828 1/20 0.54
RECQL P46063 1/20 0.54
NPSR1 Q6W5P4 1/20 0.54
NR4A1 P22736 1/20 0.45
ALDH1A1 P00352 5/20 0.39
HSP90AA1 P07900 1/20 0.39
HTT P42858 2/20 0.39
SLC6A2 P23975 2/20 0.38
ALOX15 P16050 1/20 0.38
TSHR P16473 1/20 0.38
ALOX12 P18054 1/20 0.38
PTGS1 P23219 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8060218 0.91 ALDH1A1 (0.54) MAPTL3MBTL1GAARAB9AMAPK1
SCHEMBL13945696 0.89 PPARA (0.47) MAPTL3MBTL1GAARAB9AMAPK1
SCHEMBL26746 0.84 SLC6A2 (0.44) MAPTRAB9AMAPK1KDM4ENPC1
SCHEMBL13945699 0.83 RAPGEF4 (0.45) MAPTL3MBTL1GAARAB9AMAPK1
SCHEMBL13113419 0.83 APP (0.40) MAPTL3MBTL1GAARAB9AMAPK1
SCHEMBL12164641 0.81 SLC6A2 (0.35) MAPTL3MBTL1GAARAB9AMAPK1
SCHEMBL9787388 0.81 TDP1 (0.39) MAPTL3MBTL1GAARAB9AMAPK1
SCHEMBL21622229 0.80 RAB9A (0.47) MAPTL3MBTL1GAARAB9AMAPK1
SCHEMBL13945705 0.80 MEN1 (0.41) MAPTL3MBTL1GAARAB9AMAPK1
SCHEMBL12948139 0.78 TDP1 (0.46) MAPTL3MBTL1GAATDP1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3764416-B1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO LTD (KR) 2022-01-26 EP disclosed
US-20210013420-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME, AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2021-01-14 US disclosed
EP-3764416-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF Duk San Neolux Co., Ltd. (KR) 2021-01-13 EP disclosed
US-8129467-B2 Curing accelerating compound-silica composite material, method for producing curing accelerating compound-silica composite material, curing accelerator, curable resin composition, and electronic component device HITACHI CHEMICAL CO., LTD. (JP) 2012-03-06 US disclosed
US-8013052-B2 Curable resin, production method thereof, epoxy resin composition, and electronic device HITACHI CHEMICAL COMPANY, LTD. (JP) 2011-09-06 US disclosed
US-20090062460-A1 CURING ACCELERATING COMPOUND-SILICA COMPOSITE MATERIAL, METHOD FOR PRODUCING CURING ACCELERATING COMPOUND-SILICA COMPOSITE MATERIAL, CURING ACCELERATOR, CURABLE RESIN COMPOSITION, AND ELECTRONIC COMPONENT DEVICE HITACHI CHEMICAL CO., LTD. (JP) 2009-03-05 US disclosed
US-20090023855-A1 NOVEL CURABLE RESIN, PRODUCTION METHOD THEREOF, EPOXY RESIN COMPOSITION, AND ELECTRONIC DEVICE RESONAC CORPORATION (JP) 2009-01-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210013420-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME, AND ELECTRONIC DEVICE THEREOF PIEZO1, ORAI2, OR10J3 MAPT 2975/4885L3MBTL1 540/4885GAA 3370/4885
US-20090062460-A1 CURING ACCELERATING COMPOUND-SILICA COMPOSITE MATERIAL, METHOD FOR PRODUCING CURING ACCELERATING COMPOUND-SILICA COMPOSITE MATERIAL, CURING ACCELERATOR, CURABLE RESIN COMPOSITION, AND ELECTRONIC COMPONENT DEVICE NCAPH, RAD51, H1-2 MAPT 4104/4885L3MBTL1 2830/4885GAA 4065/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.