Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.76 |
| ▸ | APEX1 | P27695 | 1/20 | 0.76 |
| ▸ | GAA | P10253 | 2/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL486184 | 0.86 | MEN1 (1.00) | MEN1KMT2AAPEX1GAACYP3A4 | |
| SCHEMBL486151 | 0.84 | GAA (1.00) | MEN1KMT2AAPEX1GAACYP3A4 | |
| SCHEMBL12869168 | 0.77 | LMNA (0.83) | MEN1KMT2AAPEX1GAACYP3A4 | |
| SCHEMBL28362332 | 0.76 | ALDH1A1 (0.74) | MEN1KMT2AGAAALDH1A1KDM4E | |
| SCHEMBL486640 | 0.76 | GAA (0.71) | MEN1KMT2AAPEX1GAACYP3A4 | |
| SCHEMBL486694 | 0.75 | LMNA (0.74) | MEN1KMT2AAPEX1GAACYP3A4 | |
| SCHEMBL14252196 | 0.73 | SMN1; SMN2 (0.66) | MEN1KMT2AAPEX1GAACYP3A4 | |
| SCHEMBL486324 | 0.72 | LMNA (1.00) | MEN1KMT2AAPEX1GAACYP3A4 | |
| SCHEMBL20016248 | 0.72 | ALDH1A1 (0.53) | MEN1KMT2AAPEX1GAALMNA | |
| SCHEMBL28910099 | 0.72 | MEN1 (0.40) | MEN1KMT2AAPEX1GAACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110713454-A | Nitro-substituted indole compound and preparation method thereof | 南京工业大学 | 2020-01-21 | — | — | CN | claimed |
| CN-110713454-B | Nitro-substituted indole compound and preparation method thereof | 南京工业大学 | 2022-12-09 | — | — | CN | disclosed |
| CN-110713454-A | Nitro-substituted indole compound and preparation method thereof | 南京工业大学 | 2020-01-21 | — | — | CN | disclosed |