Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20016815 | 0.83 | ALDH1A1 (0.49) | ALDH1A1KDM4EKMT2AHTTLMNA | |
| SCHEMBL20016250 | 0.80 | FFAR4 (0.50) | ALDH1A1HTTTSHRGAAFFAR4 | |
| SCHEMBL20016245 | 0.76 | ALDH1A1 (0.55) | ALDH1A1KMT2ALMNAGAAMAPT | |
| SCHEMBL20016247 | 0.73 | ALDH1A1 (0.46) | ALDH1A1KMT2ALMNATSHRGAA | |
| SCHEMBL12667537 | 0.71 | ALDH1A1 (0.56) | ALDH1A1KDM4EKMT2AHTTLMNA | |
| SCHEMBL20016246 | 0.69 | MEN1 (0.62) | ALDH1A1KDM4EKMT2ALMNAGAA | |
| SCHEMBL486405 | 0.68 | LMNA (0.59) | ALDH1A1KDM4EKMT2ALMNATSHR | |
| SCHEMBL2372542 | 0.67 | CA1 (0.58) | ALDH1A1KMT2ALMNAGAAMAPT | |
| SCHEMBL486153 | 0.66 | NPSR1 (0.84) | ALDH1A1KDM4EKMT2ALMNATSHR | |
| SCHEMBL2005010 | 0.66 | CA12 (0.81) | ALDH1A1KDM4EKMT2AHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9932302-B1 | N-phenyl and N-benzyl enaminones and methods for using same | UNIVERSITY OF MARYLAND EASTERN SHORE (US) | 2018-04-03 | — | — | US | disclosed |