Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Glutamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.31 |
| ▸ | GRM8 | O00222 | 1/20 | 0.31 |
| ▸ | GRM6 | O15303 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.31 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.31 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.31 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL7039217 | 0.88 | GSR (0.38) | GSRKMT2AMEN1SLC7A5 | |
| Lysine SCHEMBL7039219 | 0.88 | GSR (0.38) | GSRKMT2AMEN1SLC7A5 | |
| Glutamine SCHEMBL28290511 | 0.87 | GSR (0.38) | GSRKMT2AALOX15BLMPMP22 | |
| Lysine SCHEMBL20641479 | 0.85 | GSR (0.48) | GSRTHRBSLC7A5GRIK1SLC1A3 | |
| Lysine SCHEMBL4450695 | 0.85 | GSR (0.48) | GSRTHRBSLC7A5GRIK1SLC1A3 | |
| Lysine SCHEMBL29253065 | 0.85 | GSR (0.48) | GSRTHRBSLC7A5GRIK1SLC1A3 | |
| Glutamine SCHEMBL4294114 | 0.84 | ALOX15 (0.42) | GSRKMT2AALOX15BLMPMP22 | |
| Glutamine SCHEMBL4401454 | 0.84 | ALOX15 (0.42) | GSRKMT2AALOX15BLMPMP22 | |
| Glutamine SCHEMBL16581535 | 0.84 | GSR (0.49) | GSRKMT2AALOX15BLMPMP22 | |
| D-Glutamate SCHEMBL20213749 | 0.84 | GRM8 (0.44) | GSRKMT2AMEN1ALOX15BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115252897-B | Cartilage tissue repair scaffold capable of sequentially and continuously releasing polypeptide and factor and preparation method thereof | 北京航空航天大学 | 2023-04-07 | — | — | CN | claimed |
| CN-115252897-A | Cartilage tissue repair scaffold capable of sequentially and continuously releasing polypeptides and factors and preparation method thereof | 北京航空航天大学 | 2022-11-01 | — | — | CN | claimed |
| CN-117018280-A | Periosteum material for promoting local endogenous bone regeneration and repair and preparation method thereof | 大连医科大学附属第一医院 | 2023-11-10 | — | — | CN | disclosed |
| CN-115252897-B | Cartilage tissue repair scaffold capable of sequentially and continuously releasing polypeptide and factor and preparation method thereof | 北京航空航天大学 | 2023-04-07 | — | — | CN | disclosed |
| CN-115252897-B | Cartilage tissue repair scaffold capable of sequentially and continuously releasing polypeptide and factor and preparation method thereof | 北京航空航天大学 | 2023-04-07 | — | — | CN | disclosed |
| CN-115252897-A | Cartilage tissue repair scaffold capable of sequentially and continuously releasing polypeptides and factors and preparation method thereof | 北京航空航天大学 | 2022-11-01 | — | — | CN | disclosed |
| CN-115252897-A | Cartilage tissue repair scaffold capable of sequentially and continuously releasing polypeptides and factors and preparation method thereof | 北京航空航天大学 | 2022-11-01 | — | — | CN | disclosed |
| CN-114652892-B | Medical membrane material and preparation method thereof, uterine cavity anti-adhesion device and medical device | 上海明悦医疗科技有限公司 | 2022-09-16 | — | — | CN | disclosed |
| CN-114652892-A | Medical membrane material and preparation method thereof, uterine cavity anti-adhesion equipment and medical device | 上海明悦医疗科技有限公司 | 2022-06-24 | — | — | CN | disclosed |
| CN-110898254-B | Bioactive scaffold for repairing endometrium and improving fertility | 浙江大学 | 2021-11-30 | — | — | CN | disclosed |
| CN-110898254-A | Bioactive scaffold for repairing endometrium and improving fertility | 浙江大学 | 2020-03-24 | — | — | CN | disclosed |