Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL213340 | 0.89 | CYP1A2 (0.33) | CTSK | |
| SCHEMBL212528 | 0.87 | CYP1A2 (0.34) | — | |
| SCHEMBL209816 | 0.85 | NPC1 (0.34) | — | |
| SCHEMBL214092 | 0.85 | NPC1 (0.34) | — | |
| SCHEMBL211007 | 0.85 | NPC1 (0.33) | — | |
| SCHEMBL210909 | 0.84 | BRD4 (0.33) | — | |
| SCHEMBL213515 | 0.82 | CTSK (0.36) | CTSK | |
| SCHEMBL4353508 | 0.82 | CTSK (0.37) | CTSK | |
| SCHEMBL212341 | 0.81 | CTSK (0.37) | CTSK | |
| SCHEMBL211462 | 0.81 | CTSK (0.36) | CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2195328-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Cytokinetics, Incorporated (US) | 2010-06-16 | — | — | EP | disclosed |
| WO-2009023193-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2009-02-19 | — | — | WO | disclosed |