SCHEMBL28367018

SCHEMBL28367018

CCCNc1ccc(C(F)(c2ccc(NCCC)c(N)c2)C(F)(F)C(F)(F)F)cc1N

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.37
ALDH1A1 P00352 2/20 0.37
GAA P10253 2/20 0.37
MAPT P10636 2/20 0.37
GFER P55789 2/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
PRSS1 P07477 10/20 0.36
THRB P10828 1/20 0.34
HPGD P15428 1/20 0.34
HTT P42858 1/20 0.34
PLEC Q15149 1/20 0.34
HDAC6 Q9UBN7 1/20 0.34
TRPA1 O75762 3/20 0.33
PTGER4 P35408 2/20 0.33
CYP1A2 P05177 1/20 0.33
IDO1 P14902 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29093749 0.91 KDM4E (0.37) KDM4EALDH1A1GAAMAPTGFER
SCHEMBL3244295 0.88 MAPT (0.45) KDM4EALDH1A1GAAMAPTGFER
SCHEMBL29049650 0.85 GAA (0.52) KDM4EALDH1A1GAAMAPTGFER
SCHEMBL376223 0.85 KDM4E (0.39) KDM4EALDH1A1GAAMAPTGFER
SCHEMBL29699082 0.85 KDM4E (0.39) KDM4EALDH1A1GAAMAPTGFER
SCHEMBL356336 0.84 L3MBTL1 (0.51) KDM4EALDH1A1GAAMAPTGFER
SCHEMBL3469834 0.81 KDM4E (0.42) KDM4EALDH1A1GAAMAPTGFER
SCHEMBL28991315 0.81 KDM4E (0.36) KDM4EALDH1A1GAAMAPTGFER
SCHEMBL28401754 0.80 MEN1 (0.42) KDM4EALDH1A1GAAMAPTGFER
SCHEMBL23043792 0.77 KDM4E (0.35) KDM4EALDH1A1GAAMAPTGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112513175-B Fluoropolymer-containing composition and molded article 大金工业株式会社 2023-02-21 CN disclosed
CN-109996832-B Polymer, composition and molded article 大金工业株式会社 2022-07-01 CN disclosed
CN-114502638-A Composition containing fluoropolymer and crosslinked product 大金工业株式会社 2022-05-13 CN disclosed
CN-114456524-A Crosslinkable elastomer composition and fluororubber molded article 大金工业株式会社 2022-05-10 CN disclosed
CN-114364710-A Process for producing perfluoroelastomer and composition 大金工业株式会社 2022-04-15 CN disclosed
CN-109578581-B Seal comprising metal cover, method of making same, and method of using same 台湾积体电路制造股份有限公司 2022-03-25 CN disclosed
CN-111212874-B Crosslinkable elastomer composition and fluororubber molded article 大金工业株式会社 2022-03-04 CN disclosed
CN-113825795-A Fluoroelastomer composition and article 大金工业株式会社 2021-12-21 CN disclosed
CN-113195625-A Composition and molded article 国立大学法人秋田大学 2021-07-30 CN disclosed
CN-108473685-B Fluorine-containing silicon-containing compound 国立大学法人御茶水女子大学 2021-07-16 CN disclosed
CN-109476896-B Composition and molded article 国立大学法人秋田大学 2021-05-18 CN disclosed
CN-112543788-A Fluoropolymer-containing composition and molded article 大金工业株式会社 2021-03-23 CN disclosed
CN-112513174-A Composition, crosslinked rubber molded article, and fluoropolymer 大金工业株式会社 2021-03-16 CN disclosed
CN-112513175-A Fluoropolymer-containing composition and molded article 大金工业株式会社 2021-03-16 CN disclosed
CN-107636066-B Composition containing fluoropolymer and molded article 大金工业株式会社 2020-06-05 CN disclosed
CN-111212874-A Crosslinkable elastomer composition and fluororubber molded article 大金工业株式会社 2020-05-29 CN disclosed
CN-110709465-A Fluorine-containing elastomer composition and molded article thereof 国立大学法人东京工业大学 2020-01-17 CN disclosed