SCHEMBL3244295

SCHEMBL3244295

CCNc1ccc(C(F)(c2ccc(NCC)c(N)c2)C(F)(F)C(F)(F)F)cc1N

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.45
KDM4E B2RXH2 2/20 0.45
ALDH1A1 P00352 2/20 0.45
GAA P10253 2/20 0.45
GFER P55789 2/20 0.45
THRB P10828 1/20 0.45
HPGD P15428 1/20 0.45
HTT P42858 1/20 0.45
PLEC Q15149 1/20 0.45
LMNA P02545 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
PTPN5 P54829 1/20 0.33
KIF11 P52732 1/20 0.33
ATM Q13315 1/20 0.32
CFTR P13569 1/20 0.32
STAT3 P40763 1/20 0.32
PRSS1 P07477 2/20 0.31
TSHR P16473 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29093749 0.88 KDM4E (0.37) MAPTKDM4EALDH1A1GAAGFER
SCHEMBL28367018 0.88 KDM4E (0.37) MAPTKDM4EALDH1A1GAAGFER
SCHEMBL376030 0.84 MAPT (0.47) MAPTKDM4EALDH1A1GAAGFER
SCHEMBL29540627 0.84 MAPT (0.47) MAPTKDM4EALDH1A1GAAGFER
SCHEMBL356011 0.83 ALDH1A1 (0.54) MAPTKDM4EALDH1A1GAAGFER
SCHEMBL28401754 0.82 MEN1 (0.42) MAPTKDM4EALDH1A1GAAGFER
SCHEMBL28239300 0.80 MAPT (0.44) MAPTKDM4EALDH1A1GAAGFER
SCHEMBL28238458 0.80 KDM4E (0.44) MAPTKDM4EALDH1A1GAAGFER
SCHEMBL28370211 0.79 ALDH1A1 (0.41) MAPTKDM4EALDH1A1GAAGFER
SCHEMBL3469834 0.78 KDM4E (0.42) MAPTKDM4EALDH1A1GAAGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114456524-B Crosslinkable elastomer composition and fluororubber molded article 大金工业株式会社 2023-08-11 CN disclosed
CN-112513175-B Fluoropolymer-containing composition and molded article 大金工业株式会社 2023-02-21 CN disclosed
CN-109996832-B Polymer, composition and molded article 大金工业株式会社 2022-07-01 CN disclosed
CN-114502638-A Composition containing fluoropolymer and crosslinked product 大金工业株式会社 2022-05-13 CN disclosed
CN-114456524-A Crosslinkable elastomer composition and fluororubber molded article 大金工业株式会社 2022-05-10 CN disclosed
CN-114364710-A Process for producing perfluoroelastomer and composition 大金工业株式会社 2022-04-15 CN disclosed
CN-111212874-B Crosslinkable elastomer composition and fluororubber molded article 大金工业株式会社 2022-03-04 CN disclosed
CN-113825795-A Fluoroelastomer composition and article 大金工业株式会社 2021-12-21 CN disclosed
CN-113195625-A Composition and molded article 国立大学法人秋田大学 2021-07-30 CN disclosed
CN-108473685-B Fluorine-containing silicon-containing compound 国立大学法人御茶水女子大学 2021-07-16 CN disclosed
CN-109476896-B Composition and molded article 国立大学法人秋田大学 2021-05-18 CN disclosed
CN-112543788-A Fluoropolymer-containing composition and molded article 大金工业株式会社 2021-03-23 CN disclosed
CN-112513175-A Fluoropolymer-containing composition and molded article 大金工业株式会社 2021-03-16 CN disclosed
CN-112513174-A Composition, crosslinked rubber molded article, and fluoropolymer 大金工业株式会社 2021-03-16 CN disclosed
CN-107636066-B Composition containing fluoropolymer and molded article 大金工业株式会社 2020-06-05 CN disclosed
CN-111212874-A Crosslinkable elastomer composition and fluororubber molded article 大金工业株式会社 2020-05-29 CN disclosed
CN-110709465-A Fluorine-containing elastomer composition and molded article thereof 国立大学法人东京工业大学 2020-01-17 CN disclosed
CN-108473685-A fluorine-containing silicon-containing compound 国立大学法人御茶水女子大学 2018-08-31 CN disclosed
US-20100151254-A1 Perfluoroelastomer Compositions Including Barium Titanate Fillers GREENE, TWEED OF DELAWARE, INC. (US) 2010-06-17 US disclosed