SCHEMBL28401754

SCHEMBL28401754

CNc1ccc(C(F)(c2ccc(NC)c(N)c2)C(F)(F)C(F)(F)F)cc1N

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
HSD17B10 Q99714 2/20 0.42
ALOX15 P16050 1/20 0.42
TSHR P16473 1/20 0.42
MAPK1 P28482 1/20 0.42
ALDH1A1 P00352 4/20 0.41
KDM4E B2RXH2 2/20 0.41
GAA P10253 2/20 0.41
MAPT P10636 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
GFER P55789 1/20 0.41
PRKCI P41743 1/20 0.41
KIF11 P52732 3/20 0.36
CFTR P13569 1/20 0.34
EGFR P00533 1/20 0.32
PKM P14618 2/20 0.31
HPGD P15428 1/20 0.31
RECQL P46063 1/20 0.31
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28370211 0.83 ALDH1A1 (0.41) MEN1KMT2AHSD17B10ALOX15TSHR
SCHEMBL29539971 0.82 MEN1 (0.45) MEN1KMT2AHSD17B10ALOX15TSHR
SCHEMBL376419 0.82 MEN1 (0.45) MEN1KMT2AHSD17B10ALOX15TSHR
SCHEMBL14934058 0.82 MEN1 (0.45) MEN1KMT2AHSD17B10ALOX15TSHR
SCHEMBL3244295 0.82 MAPT (0.45) MEN1KMT2AHSD17B10ALOX15TSHR
SCHEMBL115650 0.82 ALDH1A1 (0.59) MEN1KMT2AHSD17B10ALOX15TSHR
SCHEMBL28367018 0.80 KDM4E (0.37) MEN1KMT2AALDH1A1KDM4EGAA
SCHEMBL28991341 0.78 MEN1 (0.41) MEN1KMT2AHSD17B10ALOX15TSHR
SCHEMBL28285293 0.78 MAPT (0.72) MEN1KMT2AHSD17B10ALOX15ALDH1A1
SCHEMBL20920802 0.77 ALDH1A1 (0.38) MEN1KMT2AHSD17B10ALOX15TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112543788-B Fluoropolymer-containing composition and molded article 大金工业株式会社 2023-10-24 CN disclosed
CN-112513175-B Fluoropolymer-containing composition and molded article 大金工业株式会社 2023-02-21 CN disclosed
CN-109996832-B Polymer, composition and molded article 大金工业株式会社 2022-07-01 CN disclosed
CN-114502638-A Composition containing fluoropolymer and crosslinked product 大金工业株式会社 2022-05-13 CN disclosed
CN-114456524-A Crosslinkable elastomer composition and fluororubber molded article 大金工业株式会社 2022-05-10 CN disclosed
CN-114364710-A Process for producing perfluoroelastomer and composition 大金工业株式会社 2022-04-15 CN disclosed
CN-111212874-B Crosslinkable elastomer composition and fluororubber molded article 大金工业株式会社 2022-03-04 CN disclosed
CN-113825795-A Fluoroelastomer composition and article 大金工业株式会社 2021-12-21 CN disclosed
CN-113195625-A Composition and molded article 国立大学法人秋田大学 2021-07-30 CN disclosed
CN-108473685-B Fluorine-containing silicon-containing compound 国立大学法人御茶水女子大学 2021-07-16 CN disclosed
CN-109476896-B Composition and molded article 国立大学法人秋田大学 2021-05-18 CN disclosed
CN-112543788-A Fluoropolymer-containing composition and molded article 大金工业株式会社 2021-03-23 CN disclosed
CN-112513174-A Composition, crosslinked rubber molded article, and fluoropolymer 大金工业株式会社 2021-03-16 CN disclosed
CN-112513175-A Fluoropolymer-containing composition and molded article 大金工业株式会社 2021-03-16 CN disclosed
CN-107636066-B Composition containing fluoropolymer and molded article 大金工业株式会社 2020-06-05 CN disclosed
CN-111212874-A Crosslinkable elastomer composition and fluororubber molded article 大金工业株式会社 2020-05-29 CN disclosed