SCHEMBL28367103

SCHEMBL28367103

O=C(Nc1ccccc1C(=O)Oc1ccccc1)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.59
MAPT P10636 2/20 0.59
MAPK1 P28482 1/20 0.59
ELANE P08246 3/20 0.59
PRTN3 P24158 3/20 0.59
MEN1 O00255 5/20 0.56
KMT2A Q03164 5/20 0.56
TSHR P16473 2/20 0.56
CYP1A2 P05177 1/20 0.56
CYP2D6 P10635 1/20 0.56
CYP2C19 P33261 1/20 0.56
PKM P14618 1/20 0.55
HSD17B10 Q99714 2/20 0.55
APOBEC3A P31941 1/20 0.55
APOBEC3G Q9HC16 1/20 0.55
DHODH Q02127 1/20 0.54
HPGD P15428 2/20 0.54
ALDH1A1 P00352 1/20 0.54
ALOX12 P18054 1/20 0.54
ALOX15 P16050 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11665959 0.83 TSHR (0.77) KDM4EMAPTMAPK1ELANEPRTN3
SCHEMBL28901019 0.83 KCNMA1 (0.59) KDM4EMAPTMAPK1MEN1KMT2A
SCHEMBL28480478 0.83 KCNMA1 (0.59) KDM4EMAPTMAPK1MEN1KMT2A
SCHEMBL13777318 0.82 CYP2C19 (0.60) KDM4EMAPTMAPK1KMT2ATSHR
SCHEMBL18668251 0.81 MAPT (0.56) KDM4EMAPTMAPK1ELANEPRTN3
SCHEMBL28900358 0.81 MAPT (0.56) KDM4EMAPTMAPK1ELANEPRTN3
SCHEMBL28386334 0.79 KDM4E (0.53) KDM4EMAPTMEN1KMT2ATSHR
SCHEMBL10677499 0.79 HPGD (0.51) KDM4EMAPTMAPK1ELANEPRTN3
SCHEMBL31053873 0.79 MEN1 (0.83) MAPTMAPK1MEN1KMT2APKM
SCHEMBL414754 0.79 MEN1 (0.83) MAPTMAPK1MEN1KMT2APKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108517022-B Solid catalyst component for olefin polymerization, catalyst and application thereof 北京利和知信科技有限公司 2020-10-27 CN disclosed
CN-108517021-B Solid catalyst component suitable for producing polymer with wide molecular weight distribution, catalyst and application thereof 北京利和知信科技有限公司 2020-10-27 CN disclosed
CN-105682655-B Antimicrobial compounds 阿克塞利亚制药公司 2020-03-27 CN disclosed