SCHEMBL28901019

SCHEMBL28901019

Cc1ccc(C(=O)Oc2ccccc2)c(NC(=O)c2ccccc2)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNMA1 Q12791 1/20 0.59
KDM4E B2RXH2 4/20 0.59
MAPT P10636 4/20 0.59
MAPK1 P28482 2/20 0.59
ALDH1A1 P00352 3/20 0.55
GAA P10253 2/20 0.55
GLA P06280 1/20 0.55
HPGD P15428 1/20 0.55
ATM Q13315 1/20 0.55
KMT2A Q03164 5/20 0.54
NPSR1 Q6W5P4 3/20 0.54
HSD17B10 Q99714 1/20 0.51
MEN1 O00255 4/20 0.50
PLK1 P53350 1/20 0.50
PKM P14618 1/20 0.50
GRIK1 P39086 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
GFER P55789 1/20 0.50
NR1H4 Q96RI1 1/20 0.49
CYP1A2 P05177 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27716630 0.85 KCNMA1 (0.61) KCNMA1KDM4EMAPTMAPK1ALDH1A1
SCHEMBL18668251 0.84 MAPT (0.56) KDM4EMAPTMAPK1ALDH1A1GAA
SCHEMBL28900358 0.84 MAPT (0.56) KDM4EMAPTMAPK1ALDH1A1GAA
SCHEMBL28480478 0.84 KCNMA1 (0.59) KCNMA1KDM4EMAPTMAPK1ALDH1A1
SCHEMBL28367103 0.83 KDM4E (0.59) KDM4EMAPTMAPK1ALDH1A1HPGD
SCHEMBL676149 0.80 KCNMA1 (0.66) KCNMA1MAPTHPGDATMKMT2A
SCHEMBL28471130 0.80 POLB (0.54) KCNMA1KDM4EMAPTMAPK1GAA
SCHEMBL28239332 0.80 MAPT (0.51) KDM4EMAPTMAPK1ALDH1A1GAA
SCHEMBL21771978 0.78 KMT2A (0.67) KCNMA1KDM4EMAPTMAPK1ALDH1A1
SCHEMBL16317646 0.78 KCNMA1 (0.76) KCNMA1MAPTALDH1A1HPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108517022-B Solid catalyst component for olefin polymerization, catalyst and application thereof 北京利和知信科技有限公司 2020-10-27 CN disclosed
CN-108517021-B Solid catalyst component suitable for producing polymer with wide molecular weight distribution, catalyst and application thereof 北京利和知信科技有限公司 2020-10-27 CN disclosed