SCHEMBL28367118

SCHEMBL28367118

CC(C)(C)c1ccc2c(c1)c1cc(C(C)(C)C)ccc1n2-c1cc(C#N)ccc1-c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.41
CSNK1D P48730 3/20 0.36
CSNK1G2 P78368 3/20 0.36
CCR9 P51686 1/20 0.35
DNMT1 P26358 3/20 0.35
GABRA1 P14867 2/20 0.35
GABRG2 P18507 2/20 0.35
GABRB3 P28472 2/20 0.35
GABRA5 P31644 2/20 0.35
GABRA3 P34903 2/20 0.35
GABRA2 P47869 1/20 0.35
KCNA5 P22460 1/20 0.34
PTGDR2 Q9Y5Y4 1/20 0.34
CYP19A1 P11511 1/20 0.34
CSNK1A1 P48729 1/20 0.34
GSK3B P49841 1/20 0.34
CNR1 P21554 1/20 0.34
CNR2 P34972 1/20 0.34
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28574243 0.92 KIF11 (0.50) KIF11CSNK1DCSNK1G2CCR9CYP19A1
SCHEMBL20794067 0.89 CYP1A2 (0.39) KIF11CSNK1DCSNK1G2CSNK1A1GSK3B
SCHEMBL28367816 0.89 KIF11 (0.40) KIF11PTGDR2ALDH1A1L3MBTL1
SCHEMBL23348401 0.89 KIF11 (0.42) KIF11CSNK1DCSNK1G2CCR9DNMT1
SCHEMBL20114525 0.89 ABCG2 (0.39) KIF11CSNK1DCSNK1G2CSNK1A1GSK3B
SCHEMBL22268484 0.88 ABCG2 (0.40) KIF11CSNK1DCSNK1G2CCR9GABRA1
SCHEMBL28371444 0.87 KIF11 (0.37) KIF11CSNK1DCSNK1G2CCR9DNMT1
SCHEMBL23127597 0.87 KIF11 (0.35) KIF11CSNK1DCSNK1G2CCR9DNMT1
SCHEMBL22243056 0.86 CYP1A2 (0.39) KIF11CSNK1DCSNK1G2MEN1KMT2A
SCHEMBL27016017 0.86 KIF11 (0.40) KIF11CSNK1DCSNK1G2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112638874-A Benzonitrile derivative, light-emitting material, and light-emitting element using the same 国立大学法人九州大学 2021-04-09 CN disclosed
CN-110914378-A Composition for use in organic light emitting diodes 九州有机光材股份有限公司 2020-03-24 CN disclosed