SCHEMBL28574243

SCHEMBL28574243

CC(C)(C)c1ccc2c(c1)c1cc(C(C)(C)C)ccc1n2-c1cc(C#N)ccc1-c1ccc(C#N)cc1

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 2/20 0.50
FNTA P49354 1/20 0.37
FNTB P49356 1/20 0.37
PGGT1B P53609 1/20 0.37
CSNK1D P48730 5/20 0.37
CSNK1G2 P78368 4/20 0.37
KDM1A O60341 2/20 0.37
PGR P06401 3/20 0.36
CYP19A1 P11511 1/20 0.35
CSNK1A1 P48729 1/20 0.35
GSK3B P49841 1/20 0.35
NR3C1 P04150 2/20 0.34
NR3C2 P08235 2/20 0.34
CCR9 P51686 1/20 0.34
AR P10275 1/20 0.34
CYP11B2 P19099 2/20 0.34
NR1I2 O75469 1/20 0.33
EPHX2 P34913 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28367118 0.92 KIF11 (0.41) KIF11CSNK1DCSNK1G2CYP19A1CSNK1A1
SCHEMBL24002727 0.91 KIF11 (0.51) KIF11FNTAFNTBPGGT1BCSNK1D
SCHEMBL28367117 0.88 KIF11 (0.49) KIF11FNTAFNTBPGGT1BCSNK1D
SCHEMBL18361182 0.88 KIF11 (0.47) KIF11FNTAFNTBPGGT1BCSNK1D
SCHEMBL20791973 0.88 KIF11 (0.41) KIF11FNTAFNTBPGGT1BCSNK1D
SCHEMBL20849565 0.86 KIF11 (0.39) KIF11CSNK1DCSNK1G2KDM1ACYP11B2
SCHEMBL22985313 0.86 KIF11 (0.39) KIF11CSNK1DCSNK1G2KDM1ANR3C1
SCHEMBL18361007 0.85 KIF11 (0.45) KIF11FNTAFNTBPGGT1BCSNK1D
SCHEMBL20794067 0.84 CYP1A2 (0.39) KIF11CSNK1DCSNK1G2CSNK1A1GSK3B
SCHEMBL20848917 0.84 KIF11 (0.37) KIF11CSNK1DCSNK1G2KDM1AAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112638874-A Benzonitrile derivative, light-emitting material, and light-emitting element using the same 国立大学法人九州大学 2021-04-09 CN disclosed