Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | NQO1 | P15559 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27933824 | 0.89 | FGFR1 (0.57) | HTTFGFR1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL28938202 | 0.86 | HTT (0.64) | HTTFGFR1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL695764 | 0.78 | HCAR1 (0.44) | HTTFGFR1MAPT | |
| SCHEMBL694905 | 0.77 | HTT (0.62) | HTTFGFR1SRC | |
| SCHEMBL15213044 | 0.76 | GABRP (0.55) | FGFR1ALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL701432 | 0.75 | HPGD (0.45) | HTTFGFR1ALDH1A1HPGDKDR | |
| SCHEMBL15213068 | 0.75 | FGFR1 (0.62) | HTTFGFR1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL15213048 | 0.75 | FGFR1 (0.53) | HTTFGFR1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL16393877 | 0.74 | FGFR1 (0.53) | HTTFGFR1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL29623641 | 0.72 | FGFR1 (0.75) | FGFR1ALDH1A1SMN1; SMN2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110698408-B | Antiviral drug for treatment of arenavirus infection | 奇尼塔病毒性出血热有限责任公司 | 2021-01-05 | — | — | CN | disclosed |
| CN-110776453-A | Antiviral drug for treatment of arenavirus infection | 奇尼塔四有限责任公司 | 2020-02-11 | — | — | CN | disclosed |
| CN-110698408-A | Antiviral drug for treatment of arenavirus infection | 奇尼塔四有限责任公司 | 2020-01-17 | — | — | CN | disclosed |