Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14413543 | 0.87 | DPP7 (0.57) | KMT2ANPC1LMNATDP1PKM | |
| SCHEMBL13841233 | 0.85 | MEN1 (0.72) | KMT2ASMN1; SMN2MEN1NPSR1ALDH1A1 | |
| SCHEMBL5466273 | 0.82 | KMT2A (0.76) | KMT2ANPC1SMN1; SMN2LMNATDP1 | |
| SCHEMBL30677754 | 0.82 | KMT2A (0.60) | KMT2ANPC1SMN1; SMN2RAB9ALMNA | |
| SCHEMBL28363668 | 0.81 | CHRM4 (0.61) | KMT2ANPC1SMN1; SMN2RAB9ALMNA | |
| SCHEMBL28363609 | 0.81 | MEN1 (0.62) | KMT2ANPC1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL5061039 | 0.79 | FAAH (0.64) | KMT2ANPC1SMN1; SMN2LMNATDP1 | |
| SCHEMBL12466499 | 0.79 | KMT2A (0.67) | KMT2ANPC1LMNATDP1PKM | |
| SCHEMBL11837576 | 0.78 | ALOX5 (0.69) | KMT2ANPC1SMN1; SMN2RAB9ALMNA | |
| SCHEMBL3236002 | 0.77 | GRM5 (0.58) | KMT2ASMN1; SMN2RAB9ALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110878070-B | Method for preparing asymmetric urea compound | 中国科学院化学研究所 | 2021-08-31 | — | — | CN | disclosed |
| CN-110878070-A | Method for preparing asymmetric urea compound | 中国科学院化学研究所 | 2020-03-13 | — | — | CN | disclosed |