Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23252438 | 0.85 | KMT2A (0.55) | KMT2AHRH3NPC1MEN1RAB9A | |
| SCHEMBL5466273 | 0.84 | KMT2A (0.76) | KMT2ATDP1PKMALDH1A1LMNA | |
| SCHEMBL5061039 | 0.84 | FAAH (0.64) | KMT2ATDP1PKMLMNANPC1 | |
| SCHEMBL31043861 | 0.84 | MAPT (0.55) | KMT2ATDP1PKMALDH1A1LMNA | |
| SCHEMBL5217325 | 0.83 | KDM4E (0.68) | KMT2AALDH1A1LMNAHRH3MEN1 | |
| SCHEMBL6559744 | 0.83 | KDM4E (0.68) | KMT2AALDH1A1LMNAHRH3MEN1 | |
| SCHEMBL14413543 | 0.83 | DPP7 (0.57) | KMT2ATDP1PKMALDH1A1LMNA | |
| SCHEMBL29322336 | 0.83 | KMT2A (0.54) | KMT2ATDP1ALDH1A1LMNAMAPT | |
| SCHEMBL3126965 | 0.82 | NPC1 (0.57) | KMT2AALDH1A1MAPTHRH3NPC1 | |
| SCHEMBL8225709 | 0.82 | MEN1 (0.55) | KMT2AALDH1A1HRH3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023229378-A1 | HETEROCYCLIC COMPOUND AS DIACYLGLYCEROL KINASE INHIBITOR AND USE THEREOF | 주식회사 엘지화학 | 2023-11-30 | — | — | WO | disclosed |