Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.52 |
| ▸ | CTSS | P25774 | 2/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18775042 | 1.00 | CTSK (0.52) | CTSKCTSSCTSLCTSBMEN1 | |
| SCHEMBL18775043 | 0.86 | CTSK (0.54) | CTSKCTSSCTSLCTSBS1PR4 | |
| SCHEMBL25634647 | 0.86 | CTSK (0.54) | CTSKCTSSCTSLCTSBS1PR4 | |
| SCHEMBL3969628 | 0.85 | ALDH1A1 (0.55) | MEN1ALDH1A1HTTKMT2ACA2 | |
| SCHEMBL15251810 | 0.85 | ALDH1A1 (0.55) | MEN1ALDH1A1HTTKMT2ACA2 | |
| SCHEMBL15251696 | 0.85 | ALDH1A1 (0.55) | MEN1ALDH1A1HTTKMT2ACA2 | |
| SCHEMBL24855401 | 0.84 | CTSK (0.57) | CTSKCTSSCTSLCTSB | |
| SCHEMBL18775046 | 0.84 | CTSK (0.57) | CTSKCTSSCTSLCTSB | |
| SCHEMBL10058280 | 0.84 | CASP1 (0.50) | CA12CA2CA9 | |
| SCHEMBL17792880 | 0.83 | ALDH1A1 (0.54) | CTSKCTSSCTSLMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116370448-A | Modulators of SESTRIN-GATOR2 interactions and uses thereof | 纳维托制药有限公司 | 2023-07-04 | — | — | CN | disclosed |
| CN-110809467-B | Modulators of SESTRIN-GATOR2 interactions and uses thereof | 纳维托制药有限公司 | 2023-03-10 | — | — | CN | disclosed |
| CN-110809467-A | Modulators of SESTRIN-GATOR2 interaction and uses thereof | 纳维托制药有限公司 | 2020-02-18 | — | — | CN | disclosed |