Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27528660 | 0.86 | CYP2C19 (0.54) | MAPTCYP2C19SIGMAR1ALDH1A1GAA | |
| SCHEMBL28364494 | 0.84 | CYP2C19 (0.39) | MAPTCYP2C19CYP2C9SIGMAR1KDM4E | |
| SCHEMBL28368198 | 0.78 | CYP2A13 (0.43) | SIGMAR1TDP1KDM4EALDH1A1HTT | |
| SCHEMBL28885101 | 0.77 | ALDH1A1 (0.46) | MAPTCYP2C19KDM4EALDH1A1KMT2A | |
| SCHEMBL28368317 | 0.74 | MAPT (0.46) | MAPTCYP2C19CYP2C9SIGMAR1TDP1 | |
| SCHEMBL28368564 | 0.74 | GAA (0.44) | MAPTSIGMAR1KDM4EALDH1A1GAA | |
| SCHEMBL28046393 | 0.73 | SIGMAR1 (0.47) | MAPTCYP2C19CYP2C9SIGMAR1TDP1 | |
| SCHEMBL28546647 | 0.70 | HDAC8 (0.64) | MAPTSIGMAR1KDM4EALDH1A1GAA | |
| SCHEMBL30442828 | 0.70 | HDAC8 (0.64) | MAPTSIGMAR1KDM4EALDH1A1GAA | |
| SCHEMBL28368556 | 0.70 | SIGMAR1 (0.50) | MAPTCYP2C19CYP2C9SIGMAR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107216315-B | Flavone imidazole compound and preparation method thereof | 盐城师范学院 | 2020-03-17 | — | — | CN | disclosed |