Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.43 |
| ▸ | CMA1 | P23946 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HRH2 | P25021 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27970980 | 0.84 | HRH2 (0.43) | GAASIGMAR1CMA1SMN1; SMN2HRH2 | |
| SCHEMBL28364494 | 0.82 | CYP2C19 (0.39) | SIGMAR1KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL28885101 | 0.81 | ALDH1A1 (0.46) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL27528660 | 0.81 | CYP2C19 (0.54) | GAASIGMAR1MEN1ALDH1A1MAPT | |
| SCHEMBL28368172 | 0.74 | MAPT (0.51) | GAASIGMAR1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL28364395 | 0.73 | CMA1 (0.44) | GAASIGMAR1CMA1HRH2KDM4E | |
| SCHEMBL14844570 | 0.72 | KDM4E (0.52) | GAACMA1HRH2KDM4EGSK3A | |
| SCHEMBL4771166 | 0.72 | SIGMAR1 (0.58) | SIGMAR1SMN1; SMN2HRH2 | |
| SCHEMBL27719979 | 0.72 | SIGMAR1 (0.43) | GAASIGMAR1CMA1SMN1; SMN2HRH2 | |
| SCHEMBL28496466 | 0.71 | SIGMAR1 (0.56) | SIGMAR1SMN1; SMN2MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107216315-B | Flavone imidazole compound and preparation method thereof | 盐城师范学院 | 2020-03-17 | — | — | CN | disclosed |