Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 11/20 | 0.49 |
| ▸ | DHFR | P00374 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30541339 | 1.00 | CTSA (0.49) | CTSADHFRRECQL | |
| SCHEMBL20546455 | 0.87 | CTSA (0.59) | CTSA | |
| SCHEMBL20546453 | 0.87 | CTSA (0.59) | CTSA | |
| SCHEMBL30541595 | 0.86 | FFAR1 (0.42) | CTSA | |
| SCHEMBL30541328 | 0.84 | ACLY (0.44) | — | |
| SCHEMBL28373927 | 0.84 | ACLY (0.44) | — | |
| SCHEMBL7347046 | 0.81 | ALDH1A1 (0.42) | — | |
| SCHEMBL28372548 | 0.81 | CTSA (0.43) | CTSA | |
| SCHEMBL30541542 | 0.81 | CTSA (0.43) | CTSA | |
| SCHEMBL28368832 | 0.81 | HTT (0.43) | CTSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110914242-B | Propionic acid derivatives and methods of use thereof | 阿维亚拉药品有限公司 | 2023-07-25 | — | — | CN | disclosed |
| CN-110914242-A | Propionic acid derivatives and methods of use thereof | 阿维亚拉药品有限公司 | 2020-03-24 | — | — | CN | disclosed |