Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28368267 | 0.87 | VNN1 (0.44) | NPC1ALDH1A1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL28368042 | 0.85 | KDM4E (0.40) | NPC1ALDH1A1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL28884398 | 0.84 | RXFP1 (0.45) | ALDH1A1RAB9AHPGDALOX15MAPT | |
| SCHEMBL28365163 | 0.84 | TRPV1 (0.41) | ALDH1A1MAPTSIGMAR1VNN1LMNA | |
| SCHEMBL20760484 | 0.83 | GRM1 (0.60) | NAMPTGRM5GRM1 | |
| SCHEMBL4602817 | 0.78 | ALDH1A1 (0.66) | NPC1ALDH1A1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL18009528 | 0.77 | ALDH1A1 (0.41) | NPC1ALDH1A1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL28966541 | 0.76 | TRPV1 (0.45) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL10317879 | 0.75 | ALDH1A1 (0.54) | NPC1ALDH1A1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL28443996 | 0.74 | TRPV1 (0.45) | NPC1ALDH1A1RAB9AHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117098760-A | Compositions and methods for treating KIT and PDGFRA mediated diseases | 缆图药品公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-110891953-B | Pyrrolotriazines derivatives, preparation method and application thereof | 浙江海正药业股份有限公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-110891953-A | Pyrrolotriazines derivatives, preparation method and application thereof | 浙江海正药业股份有限公司 | 2020-03-17 | — | — | CN | disclosed |