Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.33 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15540563 | 1.00 | AKR1B1 (0.37) | AKR1B1LMNAPOLBALDH1A1TAS1R3 | |
| SCHEMBL16795962 | 1.00 | AKR1B1 (0.37) | AKR1B1LMNAPOLBALDH1A1TAS1R3 | |
| SCHEMBL15540185 | 1.00 | AKR1B1 (0.37) | AKR1B1LMNAPOLBALDH1A1TAS1R3 | |
| SCHEMBL28364975 | 1.00 | AKR1B1 (0.37) | AKR1B1LMNAPOLBALDH1A1TAS1R3 | |
| SCHEMBL29015077 | 0.78 | PDK1 (0.38) | AKR1B1POLBALDH1A1KMT2AMEN1 | |
| SCHEMBL17093287 | 0.78 | PDK1 (0.38) | AKR1B1POLBALDH1A1KMT2AMEN1 | |
| SCHEMBL15539615 | 0.78 | PDK1 (0.38) | AKR1B1POLBALDH1A1KMT2AMEN1 | |
| SCHEMBL28369060 | 0.78 | PDK1 (0.38) | AKR1B1POLBALDH1A1KMT2AMEN1 | |
| SCHEMBL606119 | 0.76 | LMNA (0.44) | LMNAPOLBHSD17B10 | |
| SCHEMBL18169387 | 0.72 | SLC22A12 (0.33) | POLBLNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106507667-B | Sulfamate derivatives for the prevention or treatment of epilepsy | 比皮艾思药物研发有限公司 | 2020-01-24 | — | — | CN | disclosed |