Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28885941 | 1.00 | TP53 (0.40) | TP53ALDH1A1MAPTHPGDNPSR1 | |
| SCHEMBL28369576 | 0.84 | GAA (0.43) | ALDH1A1HPGDHSD17B10KDM4ELMNA | |
| SCHEMBL28373482 | 0.84 | GAA (0.43) | ALDH1A1HPGDHSD17B10KDM4ELMNA | |
| SCHEMBL24493150 | 0.83 | KDM4E (0.40) | TP53ALDH1A1MAPTHSD17B10KDM4E | |
| SCHEMBL16572475 | 0.82 | LMNA (0.44) | TP53ALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL16003561 | 0.82 | SMN1; SMN2 (0.43) | TP53ALDH1A1MAPTHPGDNPSR1 | |
| SCHEMBL21570164 | 0.81 | RIPK1 (0.34) | HPGDLMNA | |
| SCHEMBL24493148 | 0.80 | ALDH1A1 (0.39) | TP53ALDH1A1MAPTHPGDNPSR1 | |
| SCHEMBL19876673 | 0.79 | USP2 (0.40) | TP53MAPTHSD17B10KDM4ELMNA | |
| SCHEMBL29852659 | 0.78 | LMNA (0.36) | TP53ALDH1A1MAPTHPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110923288-A | Biological resolution method of WXFL10203614 intermediate | 卓和药业集团有限公司 | 2020-03-27 | — | — | CN | disclosed |