Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 3/20 | 0.46 |
| ▸ | PIM3 | Q86V86 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 2/20 | 0.44 |
| ▸ | RORA | P35398 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | RORB | Q92753 | 1/20 | 0.44 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11452387 | 0.91 | PGR (0.56) | PIM1PIM3ALDH1A1HPGDIMPDH2 | |
| SCHEMBL11453521 | 0.89 | PSEN1 (0.56) | PIM1PIM3ALDH1A1HPGDPGR | |
| SCHEMBL3057272 | 0.88 | ALDH1A1 (0.50) | PIM1PIM3ALDH1A1HPGDPOLB | |
| SCHEMBL11454471 | 0.79 | CYP19A1 (0.59) | ALDH1A1POLBPGRKDM4ELMNA | |
| SCHEMBL11496576 | 0.79 | ALDH1A1 (0.42) | PIM1PIM3ALDH1A1HPGDIMPDH2 | |
| SCHEMBL20363636 | 0.78 | ALKBH5 (0.61) | ALDH1A1HPGDPOLBPGRRORA | |
| SCHEMBL27943815 | 0.77 | PGR (0.49) | ALDH1A1PGRRORARORCRORB | |
| SCHEMBL28233487 | 0.76 | CNR2 (0.48) | ALDH1A1HPGDPOLBPGRRORA | |
| SCHEMBL27867696 | 0.76 | PGR (0.52) | PIM1PIM3ALDH1A1HPGDPGR | |
| SCHEMBL153959 | 0.76 | ALDH1A1 (0.62) | ALDH1A1HPGDPOLBPGRRORA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110759852-A | Preparation method of 3-hydroxymethyl-9-substituted carbazole | 陕西科技大学 | 2020-02-07 | — | — | CN | disclosed |