Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 11/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28373016 | 0.88 | MTNR1A (0.39) | PLA2G2AMTNR1AMTNR1BKMT2ANR4A2 | |
| SCHEMBL28369894 | 0.87 | NR4A2 (0.46) | KMT2ANR4A2 | |
| SCHEMBL28369467 | 0.77 | NR4A2 (0.59) | MTNR1AMTNR1BKMT2ANR4A2 | |
| SCHEMBL28369964 | 0.75 | TSHR (0.44) | KMT2ACNR1L3MBTL1 | |
| SCHEMBL28369458 | 0.74 | NR4A2 (0.45) | KMT2ANR4A2L3MBTL1 | |
| SCHEMBL28375296 | 0.71 | NR4A2 (0.44) | KMT2ANR4A2CNR1L3MBTL1 | |
| SCHEMBL28369578 | 0.71 | ALDH1A1 (0.43) | KMT2ANR4A2L3MBTL1 | |
| SCHEMBL28373390 | 0.70 | SRC (0.44) | KMT2ANR4A2 | |
| SCHEMBL28373306 | 0.70 | CREBBP (0.41) | KMT2ANR4A2L3MBTL1 | |
| SCHEMBL28691457 | 0.67 | NR4A2 (0.49) | PLA2G2AMTNR1AKMT2ANR4A2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107149602-B | Application of indole compounds and derivatives thereof in preparation of anti-HIV drugs | 中国医学科学院药物研究所 | 2020-10-09 | — | — | CN | disclosed |
| CN-107149603-B | Application of indole compounds and derivatives thereof in preparation of anti-influenza virus drugs | 中国医学科学院药物研究所 | 2020-07-14 | — | — | CN | disclosed |
| CN-107176921-B | Indole compounds with antiviral activity in isatis root and derivatives thereof | 中国医学科学院药物研究所 | 2020-03-31 | — | — | CN | disclosed |