Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 5/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28370764 | 0.82 | MAOB (0.42) | PTGS1PTGS2MAOBMT-CO2CYP2C19 | |
| SCHEMBL5099244 | 0.79 | KMT2A (0.47) | KDM4EKMT2ACYP2C9CYP2C19TSHR | |
| SCHEMBL28370600 | 0.76 | MT-CO2 (0.43) | PTGS1PTGS2MAOBMTNR1AMTNR1B | |
| SCHEMBL7037491 | 0.75 | AGBL2 (0.46) | PTGS1PTGS2MT-CO2KMT2ACYP2C9 | |
| SCHEMBL28370615 | 0.73 | AGBL2 (0.45) | PTGS1PTGS2MT-CO2CYP2C9CYP2C19 | |
| SCHEMBL9630817 | 0.71 | PTGS1 (0.45) | PTGS1PTGS2MAOBAKR1C3AKR1C2 | |
| SCHEMBL11144862 | 0.71 | HPGD (0.41) | PTGS1PTGS2MT-CO2KDM4EKMT2A | |
| SCHEMBL28560723 | 0.71 | MT-CO2 (0.39) | PTGS1PTGS2MAOBMTNR1AMTNR1B | |
| SCHEMBL7036240 | 0.70 | POLB (0.46) | PTGS1PTGS2MT-CO2KDM4EKMT2A | |
| SCHEMBL31614294 | 0.70 | MT-CO2 (0.55) | PTGS1PTGS2MAOBMT-CO2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110590737-A | Tritium-labeled zaltoprofen with high specific activity and preparation method thereof | 华中农业大学 | 2019-12-20 | — | — | CN | disclosed |