Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | BCL2 | P10415 | 2/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7037491 | 0.88 | AGBL2 (0.46) | AGBL2MT-CO2PTGS1PTGS2MMP2 | |
| SCHEMBL28370764 | 0.81 | MAOB (0.42) | ALDH1A1MT-CO2PTGS1PTGS2CYP2C19 | |
| SCHEMBL9630038 | 0.81 | AGBL2 (0.46) | AGBL2PTGS1PTGS2MMP2MMP9 | |
| SCHEMBL28375579 | 0.80 | AGBL2 (0.56) | AGBL2MT-CO2PTGS1PTGS2MMP2 | |
| SCHEMBL7036240 | 0.79 | POLB (0.46) | AGBL2ALDH1A1MT-CO2PTGS1PTGS2 | |
| SCHEMBL7708631 | 0.78 | L3MBTL1 (0.45) | AGBL2ALDH1A1MMP2MMP9MMP12 | |
| SCHEMBL28370600 | 0.75 | MT-CO2 (0.43) | MT-CO2PTGS1PTGS2L3MBTL1HPGD | |
| SCHEMBL11577641 | 0.73 | MAPT (0.50) | AGBL2ALDH1A1MMP2MMP9MMP12 | |
| SCHEMBL5148090 | 0.73 | CYP1A2 (0.51) | ALDH1A1MT-CO2PTGS1PTGS2SMN1; SMN2 | |
| SCHEMBL28370765 | 0.73 | PTGS1 (0.42) | MT-CO2PTGS1PTGS2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110590737-B | Tritium-labeled zaltoprofen with high specific activity and preparation method thereof | 华中农业大学 | 2021-04-13 | — | — | CN | claimed |
| CN-110590737-A | Tritium-labeled zaltoprofen with high specific activity and preparation method thereof | 华中农业大学 | 2019-12-20 | — | — | CN | claimed |
| CN-110590737-B | Tritium-labeled zaltoprofen with high specific activity and preparation method thereof | 华中农业大学 | 2021-04-13 | — | — | CN | disclosed |
| CN-110590737-A | Tritium-labeled zaltoprofen with high specific activity and preparation method thereof | 华中农业大学 | 2019-12-20 | — | — | CN | disclosed |