Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.58 |
| ▸ | TNKS | O95271 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30112880 | 1.00 | ADORA3 (0.58) | ADORA3TNKSALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL30112759 | 0.83 | MAPT (0.57) | ADORA3ALDH1A1SMN1; SMN2HPGDKDM4E | |
| SCHEMBL28367722 | 0.83 | MAPT (0.57) | ADORA3ALDH1A1SMN1; SMN2HPGDKDM4E | |
| SCHEMBL28367488 | 0.80 | ABCG2 (0.50) | ADORA3TNKSALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL25824715 | 0.78 | ADORA3 (0.65) | ADORA3TNKSALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL30741235 | 0.74 | ADORA3 (1.00) | ADORA3TNKSALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL31060980 | 0.74 | ADORA3 (1.00) | ADORA3TNKSALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL11734827 | 0.74 | ADORA3 (0.59) | ADORA3TNKSALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL7827471 | 0.72 | ABCG2 (0.60) | ADORA3ALDH1A1SMN1; SMN2HPGDCA1 | |
| SCHEMBL12941005 | 0.72 | MKNK2 (0.75) | ADORA3TNKSALDH1A1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110746393-B | Synthesis method of 3-methylthio substituted benzofuran compound | 河北凯诺中星科技有限公司 | 2023-01-06 | — | — | CN | disclosed |
| CN-110746393-A | Synthesis method of 3-methylthio substituted benzofuran compound | 天津大学 | 2020-02-04 | — | — | CN | disclosed |