Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 5/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28367722 | 1.00 | MAPT (0.57) | MAPTKDM4EHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL28372012 | 0.83 | ADORA3 (0.58) | MAPTKDM4EHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL30112880 | 0.83 | ADORA3 (0.58) | MAPTKDM4EHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL28367488 | 0.82 | ABCG2 (0.50) | MAPTKDM4EHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL29839958 | 0.80 | MAPT (0.63) | MAPTKDM4EHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL29171535 | 0.75 | MAPT (0.74) | MAPTKDM4EHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL31316450 | 0.75 | MAPT (0.74) | MAPTKDM4EHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL3535900 | 0.74 | KDM4E (0.82) | MAPTKDM4EHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL6244040 | 0.74 | MAPT (0.72) | MAPTKDM4EHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL7827471 | 0.73 | ABCG2 (0.60) | MAPTKDM4EHPGDALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110746393-B | Synthesis method of 3-methylthio substituted benzofuran compound | 河北凯诺中星科技有限公司 | 2023-01-06 | — | — | CN | disclosed |