Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.49 |
| ▸ | AR | P10275 | 2/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.49 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7827471 | 0.86 | ABCG2 (0.60) | ABCG2KDM4ECYP3A4KMT2ALMNA | |
| SCHEMBL30112759 | 0.82 | MAPT (0.57) | KDM4ECYP3A4KMT2ALMNATP53 | |
| SCHEMBL28367722 | 0.82 | MAPT (0.57) | KDM4ECYP3A4KMT2ALMNATP53 | |
| SCHEMBL30112880 | 0.80 | ADORA3 (0.58) | KDM4ECA1CA2ADORA3ALDH1A1 | |
| SCHEMBL30112705 | 0.80 | KDM4E (0.40) | ABCG2KDM4ECYP3A4KMT2ALMNA | |
| SCHEMBL28372012 | 0.80 | ADORA3 (0.58) | KDM4ECA1CA2ADORA3ALDH1A1 | |
| SCHEMBL28372455 | 0.80 | KDM4E (0.40) | ABCG2KDM4ECYP3A4KMT2ALMNA | |
| SCHEMBL28887974 | 0.79 | ELANE (0.46) | ABCG2KDM4ECYP3A4KMT2ALMNA | |
| SCHEMBL7876427 | 0.75 | KDM4E (0.51) | ABCG2KDM4ECYP3A4KMT2ALMNA | |
| SCHEMBL28367440 | 0.75 | KDM4E (0.55) | KDM4EKMT2ALMNAMEN1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110746393-B | Synthesis method of 3-methylthio substituted benzofuran compound | 河北凯诺中星科技有限公司 | 2023-01-06 | — | — | CN | disclosed |
| CN-110746393-A | Synthesis method of 3-methylthio substituted benzofuran compound | 天津大学 | 2020-02-04 | — | — | CN | disclosed |