Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.55 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 6/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | NQO1 | P15559 | 1/20 | 0.45 |
| ▸ | ANTXR2 | P58335 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16015217 | 0.88 | KDM4E (0.60) | MCL1HSD17B3KDM4EMEN1KMT2A | |
| SCHEMBL15842923 | 0.81 | HSD17B3 (0.60) | HSD17B3ACHEMAOBNQO1ALDH1A1 | |
| SCHEMBL17768958 | 0.79 | MCL1 (0.53) | MCL1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL9058086 | 0.79 | MCL1 (0.53) | MCL1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL10305766 | 0.77 | ALDH1A1 (0.63) | HSD17B3KDM4EMEN1KMT2AMAOB | |
| SCHEMBL12839872 | 0.77 | MAOB (0.64) | KDM4EMAPTMAOBALDH1A1SMN1; SMN2 | |
| SCHEMBL13799424 | 0.75 | MCL1 (0.52) | MCL1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL13740054 | 0.75 | CA12 (0.66) | KDM4EMAOBMAOAALDH1A1TSHR | |
| SCHEMBL29182640 | 0.75 | MAOB (0.66) | KDM4EMEN1KMT2AMAPTMAOB | |
| SCHEMBL4282429 | 0.75 | MCL1 (0.49) | MCL1ACHEMAOANQO1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110934864-A | Application of 4-methyl-6, 7-dimethoxycoumarin in preparing medicine for preventing and treating diabetic nephropathy | 佛山科学技术学院 | 2020-03-31 | — | — | CN | disclosed |