Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.53 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | NQO1 | P15559 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 4/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19147152 | 0.82 | GPR35 (0.41) | MCL1GPR35MAOBALDH1A1TSHR | |
| SCHEMBL28374261 | 0.79 | MCL1 (0.55) | MCL1MAOBALDH1A1TSHRPPARG | |
| SCHEMBL17768958 | 0.78 | MCL1 (0.53) | MCL1MAOBALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL9057890 | 0.77 | CA2 (0.64) | MAOBALDH1A1SMN1; SMN2RXFP1KDM4E | |
| SCHEMBL4282429 | 0.77 | MCL1 (0.49) | MCL1NQO1ACHEBCHEMAOA | |
| SCHEMBL2689564 | 0.77 | CA12 (0.64) | MAOBALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL26035476 | 0.77 | HSD17B3 (0.44) | GPR35MAOBNQO1MAPTCA12 | |
| SCHEMBL1406281 | 0.76 | GPR35 (0.67) | GPR35MAOBALDH1A1KDM4EHPGD | |
| SCHEMBL21457027 | 0.75 | MAOA (0.44) | MAOBKDM4EMAPTCA12CA1 | |
| SCHEMBL13740054 | 0.74 | CA12 (0.66) | GPR35MAOBALDH1A1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3553054-B1 | FLUORESCENT COUMARIN COMPOUNDS AND METHOD OF SYNTHESIS THEREOF | UNIV EVORA (PT) | 2023-01-11 | — | — | EP | disclosed |
| EP-3553054-A1 | FLUORESCENT COUMARIN COMPOUNDS AND METHOD OF SYNTHESIS THEREOF | Universidade de Évora (PT) | 2019-10-16 | — | — | EP | disclosed |
| US-20170182023-A1 | BENZOFURAN COMPOUNDS, COMPOSITIONS, KITS AND/OR METHODS THEREOF | SAVANNAH STATE UNIVERSITY | 2017-06-29 | — | — | US | disclosed |
| US-9532983-B2 | Benzofuran compounds, compositions, kits and/or methods thereof | SAVANNAH STATE UNIVERSITY (US) | 2017-01-03 | — | — | US | disclosed |
| US-20150133498-A1 | BENZOFURAN COMPOUNDS, COMPOSITIONS, KITS AND/OR METHODS THEREOF | SAVANNAH STATE UNIVERSITY | 2015-05-14 | — | — | US | disclosed |
| WO-1996012718-A1 | NOUVELLES 2-[1-(φ-PHENOXYALCOYLPIPERIDIN-4-YL)AMINOMETHYLENE]-2H-BENZOFURAN-3-ONES SUBSTITUEES, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE | PIERRE FABRE MEDICAMENT (FR) | 1996-05-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150133498-A1 | BENZOFURAN COMPOUNDS, COMPOSITIONS, KITS AND/OR METHODS THEREOF | SIGMAR1, OPRM1, OPRL1 | MCL1 3753/4885GPR35 175/4885MAOB 357/4885 |
| US-20170182023-A1 | BENZOFURAN COMPOUNDS, COMPOSITIONS, KITS AND/OR METHODS THEREOF | SIGMAR1, OPRM1, OPRL1 | MCL1 3753/4885GPR35 175/4885MAOB 357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.