Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 15/20 | 0.61 |
| ▸ | HTR2A | P28223 | 1/20 | 0.61 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.61 |
| ▸ | HTR1A | P08908 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14500078 | 0.88 | HTR2A (0.61) | MPOHTR2ATRPM8HTR1AKMT2A | |
| SCHEMBL28370930 | 0.82 | HTR2A (0.61) | HTR2ATRPM8HTR1AKMT2AGPR84 | |
| SCHEMBL763949 | 0.82 | HTR2A (0.61) | HTR2ATRPM8HTR1AGPR84SLC6A4 | |
| SCHEMBL8404321 | 0.82 | HTR2A (0.61) | HTR2AHTR1AKMT2ASLC6A4 | |
| SCHEMBL29440786 | 0.79 | HTR2A (0.64) | MPOHTR2ATRPM8HTR1AKMT2A | |
| SCHEMBL28704885 | 0.79 | HTR2A (0.64) | MPOHTR2ATRPM8HTR1AKMT2A | |
| SCHEMBL2539333 | 0.79 | SLC6A4 (0.57) | HTR1ASLC6A4 | |
| SCHEMBL2187283 | 0.78 | PKM (0.62) | MPOHTR2ATRPM8HTR1AKMT2A | |
| SCHEMBL30995725 | 0.78 | PKM (0.62) | MPOHTR2ATRPM8HTR1AKMT2A | |
| SCHEMBL27837190 | 0.77 | MPO (0.66) | MPOHTR2ATRPM8HTR1AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106986859-B | Indole derivatives and uses thereof | 广东东阳光药业有限公司 | 2020-02-11 | — | — | CN | disclosed |