Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.61 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.61 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.55 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.54 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | MMP8 | P22894 | 1/20 | 0.52 |
| ▸ | MMP14 | P50281 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.51 |
| ▸ | HTR1D | P28221 | 1/20 | 0.51 |
| ▸ | HTR1B | P28222 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28370629 | 0.88 | GPR84 (0.59) | HTR2ATRPM8GPR84SLC6A4MTNR1A | |
| SCHEMBL763949 | 0.82 | HTR2A (0.61) | HTR2ATRPM8GPR84SLC6A4MTNR1A | |
| SCHEMBL28374497 | 0.82 | MPO (0.61) | HTR2ATRPM8GPR84SLC6A4HTR1A | |
| SCHEMBL8404321 | 0.82 | HTR2A (0.61) | HTR2ASLC6A4MTNR1AMTNR1BGFER | |
| SCHEMBL30776143 | 0.82 | GPR84 (0.44) | HTR2ATRPM8GPR84SLC6A4MTNR1A | |
| SCHEMBL2539333 | 0.79 | SLC6A4 (0.57) | SLC6A4HTR1ADRD2DRD3 | |
| SCHEMBL29440786 | 0.79 | HTR2A (0.64) | HTR2ATRPM8GPR84SLC6A4MTNR1A | |
| SCHEMBL28704885 | 0.79 | HTR2A (0.64) | HTR2ATRPM8GPR84SLC6A4MTNR1A | |
| SCHEMBL2187283 | 0.78 | PKM (0.62) | HTR2ATRPM8GPR84HSD17B10HTR1A | |
| SCHEMBL30995725 | 0.78 | PKM (0.62) | HTR2ATRPM8GPR84HSD17B10HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106986859-B | Indole derivatives and uses thereof | 广东东阳光药业有限公司 | 2020-02-11 | — | — | CN | disclosed |